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  1. Nov 22, 2021 · The infectious life cycle of flaviviruses can be roughly divided into stages of binding and entry, translation and replication, assembly and release (Figure 1). For binding and entry, the virus particles first attach to the cell surface; subsequently, the viral glycoprotein E binds to a cellular receptor to initiate internalization via endocytosis.

  2. Jan 1, 2005 · Key Points. Flavivirus genomes encode three structural proteins — capsid, membrane (M, expressed as prM, the precursor to M) and envelope (E) — that constitute the virus particle. Structures ...

    • Suchetana Mukhopadhyay, Richard J. Kuhn, Michael G. Rossmann
    • 2005
  3. Jun 28, 2022 · The flavivirus particle’s life cycle includes three key steps: 1- budding into the neutral pH environment of the ER lumen; 2- transport across the trans-Golgi network (TGN), where the pH is...

  4. Oct 17, 2018 · Structure and life cycle of flaviviruses. Flaviviruses are enveloped viruses with a positive-sense, single-stranded RNA genome of ∼ 11 kb.

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