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Flavivirus, renamed Orthoflavivirus in 2023, is a genus of positive-strand RNA viruses in the family Flaviviridae.The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek virus (PCV ...
- Flavivirus
- Flaviviridae
Jun 25, 2021 · Abstract. Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil. Therapeutic drugs or vaccines for flavivirus infections are in urgent need but are not well developed. The Flaviviridae family comprises a ...
- Rong Zhao, Meiyue Wang, Jing Cao, Jing Shen, Xin Zhou, Deping Wang, Jimin Cao
- 10.3390/life11070615
- 2021
- Life (Basel). 2021 Jul; 11(7): 615.
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Flaviviridae is a family of enveloped positive-strand RNA viruses which mainly infect mammals and birds. [1] They are primarily spread through arthropod vectors (mainly ticks and mosquitoes ). [2] The family gets its name from the yellow fever virus; flavus is Latin for "yellow", and yellow fever in turn was named because of its propensity to ...
- Flasuviricetes
- Orthornavirae
- Flaviviridae
- Kitrinoviricota
Nov 22, 2021 · The first key step in the flavivirus life cycle is the attachment of viral glycoproteins to the host cell surface, followed by interaction with one or several host cell surface receptors. Flavivirus-host cell surface receptor interactions subsequently trigger virion internalisation by endocytosis . Even though attachment and entry are key steps ...
- Sophie Wilhelmina van Leur, Tiaan Heunis, Deeksha Munnur, Sumana Sanyal
- 10.1080/21505594.2021.1996059
- 2021
- Virulence. 2021; 12(1): 2814-2838.
Feb 26, 2015 · To generate the most diverse phylogenetic dataset for the flaviviruses to date, we determined the genomic sequences and phylogenetic relationships of 14 flaviviruses, of which 10 are primarily associated with Culex spp. mosquitoes. We analyze these data, in conjunction with a comprehensive collection of flavivirus genomes, to characterize flavivirus evolutionary and biogeographic history in ...
- Gregory Moureau, Shelley Cook, Philippe Lemey, Antoine Nougairede, Naomi L. Forrester, Maxim Khasnat...
- 2015
Apr 30, 2017 · 2. Origins of Flavivirus Research. In the current classification of flaviviruses (Family Flaviviridae; genus Flavivirus; type species yellow fever virus, Asibi strain) that are associated with infection of mammals, there are two main groupings of viruses: those transmitted by ticks and those transmitted by mosquitoes. The tick-borne ...
Jan 1, 2005 · Flavivirus genomes encode three structural proteins — capsid, membrane (M, expressed as prM, the precursor to M) and envelope (E) — that constitute the virus particle. Structures of several of ...
