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1 day ago · The role the prefrontal cortex plays in working memory remains controversial. Here, we tested the hypothesis that the allocation of limited resources that support working memory is strategically controlled by a visual map in the human frontal cortex. Remarkably, transcranial magnetic stimulation of retinotopically-defined superior precentral sulcus disrupted the normal allocation of resources ...
5 days ago · Introduction. Working Memory Depends on Persistent Neural Activity in the Prefrontal Cortex. Intrinsic Membrane Properties Can Generate Persistent Activity. Network Connections Can Sustain Activity. Working Memory Depends on the Modulatory Transmitter Dopamine.
Apr 26, 2024 · Cortical waves often follow preferred directions: for instance, waves formed by the alpha rhythm travel from parietal to anterior and posterior sites during rest and memory-tasks measured with...
4 days ago · Frozen tissues from the frontal cortex (BA46) were obtained from controls and patients with SCZ and BP. The tissues were weighed and homogenized in lysis buffer (50 mM HEPES, pH 8.5, 8 M urea, and ...
Apr 24, 2024 · The cerebral cortex is composed of neuronal types with diverse gene expression that are organized into specialized cortical areas. These areas, each with characteristic cytoarchitecture 1, 2,...
4 days ago · Apathy showed predominant involvement of the inferior frontal regions in AD group (a 30% decrease in CT) and of the cingulate cortex in non-AD group (a 50-60% decrease in CT). Anxiety correlated in MCI patients with the cingulate gyrus and caudate, with a CT and V decrease of about 40%, while hallucinations were associated with left enthorinal ...
2 days ago · In the frontal cortex of 5XFAD OBCS, analysis of microglial morphology revealed significant elevations in process number, process area, and the size of microglial soma compared with WT OBCS (Figure 6). Interestingly, RGFP966 incubation led to a reduction in the number of processes, an increase in the total size of microglia and a growth in the ...
