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Gentamicin is an antibiotic used to treat several types of bacterial infections. This may include bone infections, endocarditis, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, and sepsis among others. It is not effective for gonorrhea or chlamydia infections.
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Can gentamicin be used for obstetrics-gynecology infections?
Is gentamicin bactericidal?
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How is gentamicin excreted?
Apr 10, 2023 · Gentamicin is an aminoglycoside antibiotic used in the treatment of several gram-negative infections. It should be indicated based on patient age, symptoms, signs at presentation, and local antimicrobial resistance patterns to enhance the probability of successful treatment in bacterial septicemia, meningitis, urinary tract infections ...
- Bruno J. Chaves, Prasanna Tadi
- 2023/04/10
Generic name: gentamicin [ GEN-ta-MYE-sin ] Brand names: Garamycin, Cidomycin. Dosage forms: injectable solution (10 mg/mL; 40 mg/mL), intravenous solution (100 mg/100 mL-0.9%; 100 mg/50 mL-0.9%; 120 mg/100 mL-0.9%; 60 mg/50 mL-0.9%; 80 mg/100 mL-0.9%; 80 mg/50 mL-0.9%) Drug class: Aminoglycosides.
Gentamicin, an aminoglycoside with broad antimicrobial activity, is commonly used in both obstetrics and gynecology. Traditional dosing regimens for gentamicin have called for 3 times daily dosing, but recent insights into the pharmacodynamics of the drug have led to multiple studies of once-daily dosing regimens.
- Kristy Ward, Regan N. Theiler
- 10.1097/GRF.0b013e31818091cd
- 2008
- 2008/09
General. Type: Aminoglycosides. Dosage Forms: IM; IV. Common Trade Names: Genticyn, Garamycin, Gentak. Adult Dosing. All: If obese, use Adjusted Weight = IBW + 0.4 x (ABW - IBW) All: Adjust repeat dosing based on levels. General. Extended Interval. 5-7mg/kg IV q24h. First Dose: 5-7mg/kg IV. Conventional. 1-1.7mg/kg IM/IV q8h.
Gentamicin is excreted primarily by the kidneys. In patients with normal renal function, 70% or more of an initial gentamicin dose can be recovered in the urine within 24 hours. Excretion of gentamicin is significantly reduced in patients with renal impairment.
Apr 10, 2023 · Indications. Gentamicin is an aminoglycoside antibiotic. It exhibits bactericidal activity against aerobic gram-negative bacteria making gentamicin a good option to treat several common infections. [1] .