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Jan 11, 2022 · An elevated platelet count has been shown to be associated with short-term risk of cancer in the general population. 6-8 Prospective studies evaluating platelet count and survival among patients with newly diagnosed cancer have also noted a high proportion of patients who presented with thrombocytosis. 9-12 The excess risk associated with an ...
Jan 24, 2024 · A 2017 study compared 40,000 people with high platelets to 10,000 people with normal platelets and found that a high platelet count is associated with cancer risk. Specifically, males with high platelet counts were found to have an 11.6% incidence of cancer, compared to 4.1% for those without.
Jul 3, 2022 · Inflammatory conditions like autoimmune diseases, cancer or trauma, as well as certain infections and iron deficiency, are common causes of a high platelet count. Treatment is directed at the stimulus, and the platelet count returns to normal once resolved. Another reason for secondary thrombocytosis is when the spleen has been removed.
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Jan 11, 2022 · Introduction. Patients with cancer often have an abnormally high platelet count at the time of diagnosis (thrombocytosis), defined as a platelet count greater than 450 × 10 9 /L (to convert to ×10 3 per microliter, divide by 1.0). 1 A normal platelet count falls between 150 and 450 × 10 9 /L and varies with the age and sex of the individual. 1,2 Several conditions that commonly cause an ...
- 10.1001/jamanetworkopen.2021.41633
- 2022/01
- JAMA Netw Open. 2022 Jan; 5(1): e2141633.
Jan 21, 2022 · Relative to those with a medium platelet count, the rate of cancer-specific death was higher among individuals with a high platelet count (HR 1.52; 95%CI 1.48–1.55) and was lower among individuals with a low platelet count (HR 0.91; 95%CI 0.88–0.93). A high platelet count was associated with poor survival for many cancer types.
- 10.3390/cancers14030549
- 2022/02
- Cancers (Basel). 2022 Feb; 14(3): 549.
Dec 30, 2022 · Less commonly, when the high platelet count has no apparent underlying condition as a cause, the disorder is called primary thrombocythemia or essential thrombocythemia. This is a blood and bone marrow disease. A high platelet level may be detected in a routine blood test known as a complete blood count.
Feb 26, 2021 · In patients with head of pancreas cancer only, VEGF was elevated in platelets as compared to controls . Thus, changes in platelet protein content are consistently observed in patients with cancer. Interestingly, the platelet changes appear to be tumor-type-dependent as demonstrated by multiple other studies (Table (Table1). 1). The combination ...
