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  1. Hippocampus thus orchestrates memory-guided exploration that unfolds over time to build coherent memories. This new perspective on hippocampal function harmonizes with the fact that memory formation and exploratory viewing are tightly intertwined. Keywords: eye-movement tracking, fMRI, episodic, long-term, exploration.

    • PMC Free Article

      These studies have led to a new model of how the hippocampus...

    • Alzheimer’s Disease
    • Epilepsy
    • Depression and Stress

    Alzheimer’s disease may affectTrusted Source the area of the hippocampus first. Early signs of Alzheimer’s disease become noticeable when the person begins to lose their short-term memory. They may also find it difficult to follow directions. As the disease progresses, the hippocampus loses volume, and it becomes harder to function in daily life.

    Changes to the hippocampus are also associated with epilepsy. ResearchTrusted Source has found a connection between epilepsy and a difference in how the hippocampus makes new neurons. However, it is not clear whether these differences happen before or after the onset of epilepsy.

    In people with severe depression, the hippocampus hasless volume. Scientists are unsure whether the small size results from depression or if it is a contributing factor. Evidence suggests that stress may causeTrusted Sourcea negative impact on the hippocampus.

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  3. Sep 1, 2022 · Find out more about the hippocampus's role in memory processing and learn about diseases that affect this important brain structure.

  4. The hippocampus is a part of your brain that’s responsible for your memory and learning. This small structure helps you remember, both short- and long-term, and gain awareness from your environment. The hippocampus is at risk of injury or damage from underlying conditions like Alzheimer’s disease.

  5. May 20, 2022 · Johns Hopkins neuroscientists find brain mechanism tied to age-related memory loss. As the brain ages, a region in the hippocampus becomes imbalanced, causing forgetfulness. Scientists say understanding this region of the brain and its function may be the key to preventing cognitive decline. Working with rats, neuroscientists at Johns Hopkins ...

    • Rachel Wallach
  6. Nov 8, 2021 · The hippocampus has long been considered as a key structure for memory processes. Multilevel alterations of hippocampal function have been identified as a common denominator of memory impairments in a number of psychiatric and neurodegenerative diseases.

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