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  1. May 14, 2024 · Hippocampus. The hippocampus is a part of your brain that’s responsible for your memory and learning. This small structure helps you remember, both short- and long-term, and gain awareness from your environment. The hippocampus is at risk of injury or damage from underlying conditions like Alzheimer’s disease. Contents Overview Function ...

  2. Mar 13, 2015 · Abstract. Uncontrollable stress has been recognized to influence the hippocampus at various levels of analysis. Behaviorally, human and animal studies have found that stress generally impairs various hippocampal-dependent memory tasks. Neurally, animal studies have revealed that stress alters ensuing synaptic plasticity and firing properties of ...

    • Eun Joo Kim, Blake Pellman, Jeansok J. Kim
    • 10.1101/lm.037291.114
    • 2015
    • Learn Mem. 2015 Sep; 22(9): 411-416.
  3. Aug 19, 2015 · The hippocampus has provided the gateway into much of what we have learned about stress and brain structural and functional plasticity not only in adult life, but also as a result of stressors early in life. The initial focus on hippocampus has expanded to interconnected brain regions such as the amygdala, PFC, and nucleus accumbens.

    • Bruce S McEwen, Carla Nasca, Jason D Gray
    • 10.1038/npp.2015.171
    • 2016
    • 2016/01
  4. Apr 10, 2017 · With the discovery of glucocorticoid and mineralocorticoid receptors in the hippocampal formation, 13,14 a brain region involved in episodic and spatial memory and mood regulation, the hippocampus became the gateway to understanding how systemic hormones affect higher brain functions. In the hippocampus, stress and glucocorticoids were first ...

    • Bruce S. McEwen
    • 10.1177/2470547017692328
    • 2017
    • Jan-Dec 2017
  5. Feb 9, 2023 · The model hypothesizes that stress effects on the hippocampus is a product of the medial prefrontal cortex (mPFC) transmitting an inhibitory function of controllability, f(C), the amygdala (AMYG ...

  6. Abstract. The hippocampus provided the gateway into much of what we have learned about stress and brain structural and functional plasticity, and this initial focus has expanded to other interconnected brain regions, such as the amygdala and prefrontal cortex. Starting with the discovery of adrenal steroid, and later, estrogen receptors in the ...

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  8. Jun 1, 2002 · The influence that stress neuromodulators (variable s) have on the hippocampus is a function of their direct effects on the hippocampus, denoted by h(s), and the effects of these neuromodulators ...

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