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Mature Entamoeba histolytica/Entamoeba dispar cysts have 4 nuclei that characteristically have centrally located karyosomes and fine, uniformly distributed peripheral chromatin. Cysts usually measure 12 to 15 µm.
Entamoeba cells are small, with a single nucleus and typically a single lobose pseudopod taking the form of a clear anterior bulge. They have a simple life cycle. The trophozoite (feeding-dividing form) is approximately 10-20 μm in diameter and feeds primarily on bacteria. It divides by simple binary fission to form two smaller daughter cells.
- Entamoeba, Casagrandi & Barbagallo, 1897
- Entamoebidae
Jan 28, 2021 · Entamoeba histolytica is a human enteric protozoan parasite responsible for the disease amebiasis. Infection starts through the ingestion of E. histolytica cysts contaminating food or water. The vast majority (90%) of infected individuals are asymptomatic carriers in which the parasite resides firmly within the lumen of the colon and excrete cysts in stool to complete the direct life cycle. In ...
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Its body is covered by plasma lemma and cytoplasm is differentiated into ectoplasm and endoplasm. There is a single large, broad and blunt pseudopodium formed of ectoplasm. Endoplasm contains single spherical nucleus and food vacuoles. Nucleus has peripheral crown of chromatin blocks and a centrally located nucleolus.
Ingested RBC; distinctive nucleus Cyst Stage: Chromatoidal body 'Cigar' shaped bodies (made up of crystalline ribosomes) Number of nuclei: 1 in early stages, 4 when mature Pathognomonic/diagnostic feature 'Ring and dot' nucleus and chromatoid bodies
- E. histolytica
- Entamoeba
Entamoeba histolytica/Entamoeba dispar trophozoites have a single nucleus and usually measure 15 to 20 µm (range 10 to 60 µm), tending to be more elongated in diarrheal stool. Figure A: Trophozoite of E. histolytica/E. dispar in a direct wet mount stained with iodine.
Entamoeba histolytica is the causative agent of amebiasis, a disease that is a major source of morbidity and mortality in the developing world. The potent cytotoxic activity of the parasite appears to underlie disease pathogenesis, although the mechanism is unknown. Recently, progress has been made in determining that the parasite activates apoptosis in target cells and some putative effectors ...
