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Aug 28, 2024 · In this study, Sam Gerard learned to grow Entamoeba histolytica and purified the lectin directly from these cells. He then used cryogenic electron microscopy to see what the lectin looks like and to identify the carbohydrate binding site.
6 hours ago · The cell membrane is a fundamental component of bacterial cells, acting as a dynamic barrier that regulates the movement of substances in and out of the cell. Composed primarily of a phospholipid bilayer interspersed with proteins, the membrane serves as a selective permeability barrier, allowing essential nutrients to enter while waste ...
3 days ago · nucleus, in biology, a specialized structure occurring in most cells (except bacteria and blue-green algae) and separated from the rest of the cell by a double layer, the nuclear membrane.
- The Editors of Encyclopaedia Britannica
Sep 12, 2024 · The cell nucleus contains the majority of the cell's genetic material in the form of multiple linear DNA molecules organized into structures called chromosomes. Each human cell contains roughly two meters of DNA.
3 days ago · STING-mediated TFEB activation is independent of TBK1, but it requires STING trafficking and its conserved proton channel. GABARAP lipidation, stimulated by the channel of STING, is key for STING-dependent TFEB activation. STING stimulates global upregulation of TFEB-target genes, mediating lysosomal biogenesis and autophagy.
3 days ago · We used human BJ fibroblasts for these experiments, as they have endogenous cGAS-STING signaling and are commonly used for mechanistic studies of this pathway. 21, 22, 23 This approach allowed us to capture proteins that were initially biotinylated in the cytosol but enriched in the nucleus after STING activation (Figures 1 B, S1 A, and S1B).
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4 days ago · The bacterial cell envelope is a complex multilayered structure conserved across all bacterial phyla. It is categorized into two main types based on the number of membranes surrounding the cell.
