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Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. [1] Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. [1] E. histolytica infection is estimated to kill more than 55,000 people each year. [2]
- E. histolytica
- Entamoeba
Dec 2, 2018 · Entamoeba histolytica is an invasive enteric protozoan [1, 2, 10]. Infection typically begins with the ingestion of mature, quadrinucleated cysts found in fecally contaminated food or water. Excystation occurs in the small intestine with the release of motile trophozoites, which migrate to the large intestine.
- Micaella Kantor, Anarella Abrantes, Andrea Estevez, Alan Schiller, Jose Torrent, Jose Gascon, Robert...
- 2018
Nov 29, 2020 · Entamoeba histolytica is the etiological agent of amebiasis in humans. This ameba parasite resides as a commensal in the intestine where it shares intestinal resources with the bacterial microbiome. In the intestinal ecosystem, the ameba encysts and eventually develops disease by invading the tissues. E. histolytica possesses cell surface ...
- Nancy Guillen
- 2021
Mature Entamoeba histolytica/Entamoeba dispar cysts have 4 nuclei that characteristically have centrally located karyosomes and fine, uniformly distributed peripheral chromatin. Cysts usually measure 12 to 15 µm.
Oct 31, 2022 · Entamoeba histolytica is a protozoan parasite that is the causative agent of amoebiasis. This parasite has caused widespread infection in India, Africa, Mexico, and Central and South America, and results in 100,000 deaths yearly. An immune response is ...
- 10.3390/membranes12111079
- 2022/11
- Membranes (Basel). 2022 Nov; 12(11): 1079.
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Jun 3, 2020 · Immune defenses against Entamoeba histolytica. In the lumen of the large intestine, glycosidases and proteinases secreted from amoebas are involved in the degradation of mucin mucus layer (blue). The proteinase EhCP-A5 binds to and activates integrins on endothelial cells, leading to NLRP3 inflammasome formation.
Entamoeba cells are small, with a single nucleus and typically a single lobose pseudopod taking the form of a clear anterior bulge. They have a simple life cycle. The trophozoite (feeding-dividing form) is approximately 10-20 μm in diameter and feeds primarily on bacteria.
