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- Miescher subjected the purified nuclei to an alkaline extraction followed by acidification, resulting in the formation of a precipitate that he called nuclein (now known as DNA). Miescher found that this contained phosphorus and nitrogen, but not sulfur.
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Apr 22, 2013 · 1869: DNA First Isolated. Friedrich Miescher isolates DNA for the first time. Miescher, a Swiss scientist, wanted to study the chemistry of cells. He chose to study white blood cells, which are abundant in pus, and were abundantly available to him in bandages from a hospital near his university.
Feb 15, 2005 · Based on his results on the differentiation of oocytes and spermatozoa, over the years Miescher developed a range of theories attempting to explain the processes of fertilization (Miescher, 1872c, Miescher, 1874b, Miescher, 1892b, Miescher, 1892c, Miescher, 1895) and the transmission of hereditary traits (Miescher, 1892c, Miescher, 1893c ...
- Ralf Dahm
- 2005
Mar 27, 2024 · In 1869, while working under Ernst Hoppe-Seyler at the University of Tübingen, Miescher discovered a substance containing both phosphorus and nitrogen in the nuclei of white blood cells found in pus. The substance, first named nuclein because it seemed to come from cell nuclei, became known as nucleic acid after 1874, when Miescher separated ...
- The Editors of Encyclopaedia Britannica
Miescher subjected the purified nuclei to an alkaline extraction followed by acidification, resulting in the formation of a precipitate that he called nuclein (now known as DNA). Miescher found that this contained phosphorus and nitrogen, but not sulfur.
- University of Göttingen (M.D. 1868), University of Lepzig
- Swiss
- Discovery of nucleic acidly s
- Biology
Although James Watson and Francis Crick determined the double-helical structure of DNA, DNA itself was identified nearly 90 years earlier by Swiss chemist Friedrich Miescher.
Feb 15, 2005 · Choosing leucocytes as his source material, he first investigated the proteins in these cells. However, during these experiments, he noticed a substance with unexpected properties that did not match those of proteins. Miescher had obtained the first crude purification of DNA.
This article reviews the events and circumstances leading to Miescher's discovery of DNA and places them within their historic context. It also tries to elucidate why it was Miescher who discovered DNA and why his name is not universally associated with this molecule today.
