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Oct 25, 2010 · Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.
- Overview
- Symptoms
- Causes
- Risk Factors
- Complications
- Prevention
Dengue (DENG-gey) fever is a mosquito-borne illness that occurs in tropical and subtropical areas of the world. Mild dengue fever causes a high fever and flu-like symptoms. The severe form of dengue fever, also called dengue hemorrhagic fever, can cause serious bleeding, a sudden drop in blood pressure (shock) and death. Millions of cases of dengue...
Many people experience no signs or symptoms of a dengue infection. When symptoms do occur, they may be mistaken for other illnesses — such as the flu — and usually begin four to 10 days after you are bitten by an infected mosquito. Dengue fever causes a high fever — 104 F (40 C) — and any of the following signs and symptoms: 1. Headache 2. Muscle, ...
Dengue fever is caused by any one of four types of dengue viruses. You can't get dengue fever from being around an infected person. Instead, dengue fever is spread through mosquito bites. The two types of mosquitoes that most often spread the dengue viruses are common both in and around human lodgings. When a mosquito bites a person infected with a...
You have a greater risk of developing dengue fever or a more severe form of the disease if: 1. You live or travel in tropical areas.Being in tropical and subtropical areas increases your risk of exposure to the virus that causes dengue fever. Especially high-risk areas include Southeast Asia, the western Pacific islands, Latin America and Africa. 2...
Severe dengue fever can cause internal bleeding and organ damage. Blood pressure can drop to dangerous levels, causing shock. In some cases, severe dengue fever can lead to death. Women who get dengue fever during pregnancy may be able to spread the virus to the baby during childbirth. Additionally, babies of women who get dengue fever during pregn...
Vaccine
In areas of the world where dengue fever is common, one dengue fever vaccine (Dengvaxia) is approved for people ages 9 to 45 who have already had dengue fever at least once. The vaccine is given in three doses over the course of 12 months. The vaccine is approved only for people who have a documented history of dengue fever or who have had a blood test that shows previous infection with one of the dengue viruses — called seropositivity. In people who have not had dengue fever in the past (ser...
Prevent mosquito bites
The World Health Organization stresses that the vaccine is not an effective tool on its own to reduce dengue fever in areas where the illness is common. Preventing mosquito bites and controlling the mosquito population are still the main methods for preventing the spread of dengue fever. If you live in or travel to an area where dengue fever is common, these tips may help reduce your risk of mosquito bites: 1. Stay in air-conditioned or well-screened housing.The mosquitoes that carry the deng...
Jun 13, 2019 · In humans, DENV infection causes dengue fever (DF) and in severe cases, dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). In the transmission cycle, upon injection into the human body, the virus gains entry into the host’s cells, hijacks the host’s cell machinery to replicate, and escapes the host’s immune strategies to ...
- Debica Mukherjee, Sandeepan Das, Feroza Begum, Sweety Mal, Upasana Ray
- 10.3390/pathogens8020077
- 2019
- Pathogens. 2019 Jun; 8(2): 77.
The spread of the dengue virus results in viremia, which is a high level of the virus in the bloodstream. To fight the infection, the immune system produces antibodies to neutralize the...
- Dengue viruses are spread to people through the bite of an infected Aedes species (Ae. aegypti or Ae. albopictus) mosquito. These mosquitoes also spread Zika, chikungunya, and other viruses.
- Dengue is common in more than 100 countries around the world.
- Forty percent of the world’s population, about 3 billion people, live in areas with a risk of dengue. Dengue is often a leading cause of illness in areas with risk.
- Each year, up to 400 million people get infected with dengue. Approximately 100 million people get sick from infection, and 22,000 die from severe dengue.
Jun 6, 2022 · Diseases & Conditions / Dengue Fever. Dengue fever is an illness spread by the bite of mosquitos infected with one of the dengue viruses. Symptoms are usually flu-like but can worsen to severe dengue (dengue hemorrhagic fever), a life-threatening condition. Getting infected a second time increases your risk of serious symptoms.
The human body's immune system is the primary defense against the dengue virus. When someone is infected with dengue, the body's innate and adaptive immune responses work together to...
