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1. www.mayoclinic.org › diseases-conditions › dengueDengue fever - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › dengue

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   Oct 5, 2022 · Dengue fever is caused by any one of four types of dengue viruses. You can't get dengue fever from being around an infected person. Instead, dengue fever is spread through mosquito bites. The two types of mosquitoes that most often spread the dengue viruses are common both in and around human lodgings.

2. www.nih.gov › how-dengue-virus-infects-cellsHow Dengue Virus Infects Cells | National Institutes of ...

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   Oct 25, 2010 · Researchers have discovered a key step in how the dengue virus infects a cell. The finding will allow researchers to study the process in the laboratory and provide a valuable tool for testing new drugs to prevent or treat infection. The virus that causes dengue is transmitted by mosquitoes.

3. People also ask

   How does the dengue virus get into a cell?

   • Each year, the virus infects up to 100 million people and kills about 22,000, most of them children. To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.

   How Dengue Virus Infects Cells - National Institutes of Health (NIH)

   www.nih.gov/news-events/nih-research-matters/how-dengue-virus-infects-cells

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   What causes dengue infection?

   • Dengue infection can lead to the generation of autoantibodies against DENV NS1antigen, DENV prM, and E proteins, which can cross-react with several self-antigens such as plasminogen, integrin, and platelet cells. Apart from viral factors, several host genetic factors and gene polymorphisms also have a role to play in pathogenesis of DENV infection.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   How does the dengue virus affect white blood cells?

   • Normally, monocytes and macrophages ingest and destroy pathogens, but instead of destroying the dengue virus, both types of white blood cells are targeted and infected by the virus. The dengue virus tricks the immune system to get around its defenses and infect more cells.

   Host Response to the Dengue Virus | Learn Science at Scitable - Nature

   www.nature.com/scitable/topicpage/host-response-to-the-dengue-virus-22402106/

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4. my.clevelandclinic.org › health › diseasesDengue Fever: Causes, Symptoms & Treatment - Cleveland Clinic

   my.clevelandclinic.org › health › diseases

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   Jun 6, 2022 · What causes dengue fever? Dengue fever is caused by one of four dengue viruses. When a mosquito infected with the dengue virus bites you, the virus can enter your blood and make copies of itself. The virus itself and your immune system’s response can make you feel sick.

5. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

6. www.nature.com › scitable › topicpageHost Response to the Dengue Virus | Learn Science at Scitable

   www.nature.com › scitable › topicpage

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   Introduction. Dengue viral infections can result in a range of symptoms. Some people show no symptoms or just have mild signs of the disease, but others develop severe complications. How does...

7. www.ncbi.nlm.nih.gov › pmc › articlesDengue virus and the host innate immune response - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 10, 2018 · The viral life cycle of dengue virus (DENV). The virus binds to host cell receptors (exact receptors are unknown) (1) and enters the host cell (DENV permissive cells include keratinocytes, dendritic cells, endothelial cells, fibroblasts, macrophage, and mast cells), via receptor-mediated endocytosis (2).

8. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus Infection: A Tale of Viral Exploitations and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 30, 2021 · Severe Dengue virus infection causes tenderness and belly pain, vomiting at least thrice a day, epistaxis, hematemesis, melena, fatigue, and restlessness, which finally lead to hemorrhagic fever and organ failure [ 2 ]. Four different serotypes of the Dengue virus are found worldwide.