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Sep 30, 2021 · Abstract. Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one of the prominent public health problems in tropical and subtropical regions with no effective vaccines. Every year around 400 million people get infected by the Dengue virus, with a mortality rate of about 20% among the patients with severe dengue.
As the infected monocytes and macrophages travel through the lymphatic system, the dengue virus spreads throughout the body. During its journey, the dengue virus infects more cells,...
Oct 5, 2022 · Dengue fever causes a high fever — 104 F (40 C) — and any of the following signs and symptoms: Headache; Muscle, bone or joint pain; Nausea; Vomiting; Pain behind the eyes; Swollen glands; Rash; Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening.
Oct 10, 2018 · The virus binds to host cell receptors (exact receptors are unknown) (1) and enters the host cell (DENV permissive cells include keratinocytes, dendritic cells, endothelial cells, fibroblasts, macrophage, and mast cells), via receptor-mediated endocytosis (2).
Feb 16, 2024 · Dengue fever is a potentially life-threatening viral infection transmitted through the bite of infected mosquitoes. "Four different subtypes of the virus can cause infections in humans," says Dr. Stacey Rizza, a Mayo Clinic infectious diseases specialist.
Jun 6, 2022 · Dengue fever is caused by one of four dengue viruses. When a mosquito infected with the dengue virus bites you, the virus can enter your blood and make copies of itself. The virus itself and your immune system’s response can make you feel sick.
To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.
