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  1. Oct 25, 2010 · To infect a cell, the dengue virus initially binds to the cell surface. It gains entry into the cell when it becomes enveloped by the cell membrane during the creation of a pouch-like structure known as an endosome.

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  3. Dengue infections are caused by four closely related viruses. How do dengue viruses infect human cells and replicate themselves?

  4. Dec 15, 2021 · DENV infection inductees after the attachment of the dengue virus to the target cell through interfaces between the various cell surface receptors and viral envelope (E) protein . In mammalian cells, all categorized serotypes interact with mannose, heparan sulfate, nLc4Cer, and DC-SIGN/L-SIGN receptors.

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  5. Nov 24, 2020 · The pathogenesis of dengue was attributed to various viral and host factors such as non-structural protein 1 (NS1) viral antigen, DENV genome variation, subgenomic RNA, antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies and autoimmunity.

    • Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
    • 10.1007/s00284-020-02284-w
    • 2021
    • Curr Microbiol. 2021; 78(1): 17-32.
  6. Sep 30, 2021 · Here in this review article, we will be discussing different stages of the Dengue virus infection cycle inside mammalian host cells and how host proteins are exploited by the virus in the course of infection as well as how the host counteracts the virus by eliciting different antiviral responses.

    • Nikita Nanaware, Anwesha Banerjee, Satarupa Mullick Bagchi, Parikshit Bagchi, Anupam Mukherjee
    • 10.3390/v13101967
    • 2021
    • Viruses. 2021 Oct; 13(10): 1967.
  7. To infect a cell, dengue virus (counterclockwise, from upper left) binds to the cell membrane. The virus is then enveloped in the membrane, which coalesces around it, forming a pouch-like structure called an endosome.

  8. Jun 24, 2016 · New research findings are shedding light on the mechanisms of dengue infection, such as how the virus enters the cells and how the human immune system responds to dengue infection. Other NIAID projects are identifying the human and viral factors that determine and contribute to the severity and transmissibility of this disease.

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