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1. journals.plos.org › plosone › articleTargetDB: A target information aggregation tool and ... - PLOS

   journals.plos.org › plosone › article

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   Sep 2, 2020 · Data used in TargetDB comes from a variety of sources. Some data comes from pre-aggregated/processed data from other databases such as UniProt or TCRD. While others come directly from the source API’s such as Human Protein Atlas for protein expression levels and Open Targets for disease association.

2. www.ncbi.nlm.nih.gov › pmc › articlesTherapeutic target database update 2022: facilitating drug ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 1, 2022 · While the established databases provide the comprehensive information of both drugs and targets , there is an inadequate coverage of the comparative data for the targeted agents and high-confidence 3D structures of human targets.

   • DOI: 10.1093/nar/gkab953

   • Published: 2022/01/01

3. People also ask

   Where does targetdb data come from?

   • Data used in TargetDB comes from a variety of sources. Some data comes from pre-aggregated/processed data from other databases such as UniProt or TCRD. While others come directly from the source API’s such as Human Protein Atlas for protein expression levels and Open Targets for disease association.

   TargetDB: A target information aggregation tool and tractability predict…

   journals.plos.org/plosone/article?id=10.1371/journal.pone.0232644

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   Can a target database be maintained on a different system?

   • It is typical for the target database for a host system to reside on the same volume as the host database on the host system. Target databases usually are created and maintained on their respective target systems. However, the target databases can also be maintained on a different system if an Expand connection exists to the target system.

   Target Database - an overview | ScienceDirect Topics

   www.sciencedirect.com/topics/computer-science/target-database

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   What is therapeutic target database update 2022?

   • Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents. Drug discovery is promoted by not only the knowledge of drugs ( 1) and their therapeutic targets ( 2–4 ), but also the comparative data with respect to other bioactive agents and other targets.

   Therapeutic target database update 2022: facilitating drug discovery

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8728281/

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   Does targetdb support aggregation of data?

   • Although resources such as UniProt, Pharos/TCRD and Open Targets already propose some aggregation of data, we propose with TargetDB to complement them with additional information such as structurally enabled druggability assessment, area-specific scoring for agile prioritization and a tractability prediction model.

   TargetDB: A target information aggregation tool and tractability predict…

   journals.plos.org/plosone/article?id=10.1371/journal.pone.0232644

   See all results for this question

4. pubmed.ncbi.nlm.nih.gov › 32877430TargetDB: A target information aggregation tool and ... - PubMed

   pubmed.ncbi.nlm.nih.gov › 32877430

   Sep 2, 2020 · To address this challenge, we developed TargetDB, a tool that aggregates public information available on given target (s) (links to disease, safety, 3D structures, ligandability, novelty, etc.) and assembles it in an easy to read output ready for the researcher to analyze.

   • Author: Stephane De Cesco, John B. Davis, Paul E. Brennan

   • Publish Year: 2020

5. pubmed.ncbi.nlm.nih.gov › 34718717Therapeutic target database update 2022: facilitating drug ...

   pubmed.ncbi.nlm.nih.gov › 34718717

   Jan 7, 2022 · Drug discovery relies on the knowledge of not only drugs and targets, but also the comparative agents and targets. These include poor binders and non-binders for developing discovery tools, prodrugs for improved therapeutics, co-targets of therapeutic targets for multi-target strategies and off-targ ….

6. www.ncbi.nlm.nih.gov › pmc › articlesSwissTargetPrediction: updated data and new features for ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jul 2, 2019 · The planned extension of interoperability by including other in-house tools is an on-going work and therefore additional icons will be added in the different websites in the future. Also, the use of the molecule as potential input to other, possibly external, methods is facilitated by obtaining its SMILES through a click on the fourth icon.

   • Author: Antoine Daina, Olivier Michielin, Olivier Michielin, Vincent Zoete, Vincent Zoete
   • DOI: 10.1093/nar/gkz382

   • Publish Year: 2019
   • Published: 2019/07/07

7. www.sciencedirect.com › target-databaseTarget Database - an overview | ScienceDirect Topics

   www.sciencedirect.com › target-database

   Target databases usually are created and maintained on their respective target systems. However, the target databases can also be maintained on a different system if an Expand connection exists to the target system. View chapter Explore book.