Search results
Von Willebrand Disease (VWD), the most common inherited bleeding disorder, is defined by decreased activity of von Willebrand Factor (VWF) activity in the blood. This can be secondary to a quantitative or qualitative defect.
- Angela C. Weyand, Veronica H. Flood
- 2021/12
- 10.1016/j.hoc.2021.07.004
People also ask
How is von Willebrand disease (vWD) diagnosed?
What are the signs and symptoms of von Willebrand disease (vWD)?
What is von Willebrand disease (vWD)?
Mar 26, 2015 · Current standard practice in the laboratory diagnosis for VWD relies on 2 VWF-specific tests that evaluate (1) the quantity of VWF that is present in plasma, and (2) the efficacy of this plasma VWF in its ability to bind platelets in the presence of the antibiotic ristocetin.
- Christopher Ng, Christopher Ng, David G. Motto, Jorge Di Paola, Jorge Di Paola
- 2015
May 15, 2024 · Key Points. Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. VWD is the most common bleeding disorder. Signs of VWD include nosebleeds, easy bruising, heavy menstrual bleeding, and longer than normal bleeding after injury, surgery, dental work, or childbirth. What it is.
Mar 13, 2024 · The diagnosis of VWD involves three elements: (i) a personal history of excessive mucocutaneous bleeding, often obtained now through the application of a bleeding assessment tool 2; (ii) coagulation laboratory findings consistent with reduced levels and/or dysfunction of VWF, and (iii) a family history of a bleeding problem.
Jan 18, 2024 · von Willebrand disease (VWD) is the most common bleeding disorder and especially milder type 1 VWD might not be cared for in specialty clinics. VW factor levels rise with age, but the rise of these levels does not necessarily correlate with bleeding risk.
Von Willebrand Disease is a blood disorder in which the blood does not clot properly. Learn More.
Nov 29, 2018 · Summary. Autosomal inheritance with variable penetrance and phenotypic expression. Usually presents with mucocutaneous bleeding. Menorrhagia and postpartum hemorrhage common in affected females. Joint bleeding rare and seen only in patients with more severe disease.
