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1. www.ncbi.nlm.nih.gov › pmc › articlesDengue Virus

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 20, 2019 · Abstract. Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus.

   • Clinical Manifestations and Management of Dengue/DHF/DSS

     The disease is caused by dengue viruses that have four...

   • Figure 16.7

     Dengue virus (DENV) belongs to the family Flaviviridae,...

   • A Case Control Study

     Notably, dengue serotype 2 was known to be associated with...

   • What If

     Ghiasi H, Cai S, Slanina S, Nesburn AB, Wechsler SL....

   • 5-Year Multi-Center Retrospective Study

     Background. Dengue is the most important arthropod-borne...

   • Clinical Features of Dengue in a Large Vietnamese Cohort

     Dengue is a common and potentially serious viral illness....

2. www.ncbi.nlm.nih.gov › pmc › articlesStructural landscape of the complete genomes of dengue virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   May 17, 2021 · Our massive computational analysis provided novel results regarding the secondary structure and the interaction with human proteins, not only for DENV serotypes, but also for other flaviviruses and viral hemorrhagic fevers-associated viruses.

   • Author: Riccardo Delli Ponti, Marek Mutwil
   • DOI: 10.1186/s12864-021-07638-7

   • Publish Year: 2021
   • Publication: BMC Genomics. 2021; 22: 352.

3. People also ask

   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   How many proteins are in the dengue virus genome?

   • The dengue virus genome. The ~10.7 kb DENV genome encodes three structural proteins (capsid [ C ], premembrane [ prM ], and envelope [ E ]) and seven non-structural ( NS) proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). UTR untranslated region

   Genomic approaches for understanding dengue: insights from the virus

   genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0907-2

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   Does a single nucleotide polymorphism protect against severe dengue?

   • The genotype of an single nucleotide polymorphism (SNP) at position 352 of the VDR gene was associated with protection from severe dengue ( Loke et al., 2002 ). They also showed that homozygotes for the arginine variant at position 131 of the Fcγ receptor (FcγR) II gene appeared to be protected from the development of severe DENV infection.

   Dengue Virus - PMC - National Center for Biotechnology Information

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7149978/

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4. www.cdc.gov › dengue › hcpClinical Features of Dengue | Dengue | CDC

   www.cdc.gov › dengue › hcp

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   May 14, 2024 · Key points. About 1 in 4 dengue virus infections are symptomatic. Approximately 1 in 20 patients with dengue progress to develop severe, life-threatening disease called severe dengue. Because there are four dengue viruses, people can be infected with DENV multiple times in their life.

5. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · Dengue is a mosquito-borne Flavivirus infection, primarily transmitted by Aedes aegypti followed by Aedes albopictus mosquito and other species of genus Aedes [ 1, 4]. There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 [ 5 ].

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

6. pubmed.ncbi.nlm.nih.gov › 34171205Dengue virus: epidemiology, biology, and disease aetiology

   pubmed.ncbi.nlm.nih.gov › 34171205

   Abstract. Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions.

   • Author: Sudipta Kumar Roy, Soumen Bhattacharjee

   • Publish Year: 2021

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8. www.sciencedirect.com › science › articleDengue overview: An updated systemic review - ScienceDirect

   www.sciencedirect.com › science › article

   Oct 1, 2023 · open access. Abstract. Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed.

9. genomebiology.biomedcentral.com › articles › 10Genomic approaches for understanding dengue: insights from ...

   genomebiology.biomedcentral.com › articles › 10

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   Jun 11, 2015 · Within each of the four DENV serotypes, which share ~65–70 % amino acid sequence similarity [ 20 ], virus strains are further classified into distinct genotypes, which can vary by ~6–8 % at the nucleotide level and by 3 % at the amino acid level [ 21 – 24 ].