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The dengue virus is a roughly spherical structure composed of the viral genome and capsid proteins surrounded by an envelope and a shell of proteins. After infecting a host cell, the dengue virus ...
Dengue virus. Dengue virus ( DENV) is the cause of dengue fever. It is a mosquito -borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
- Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
- 10.1007/s00284-020-02284-w
- 2021
- Curr Microbiol. 2021; 78(1): 17-32.
Sep 20, 2019 · Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus includes other arthropod borne viruses such as yellow fever virus, West Nile virus, Zika virus, tick-borne encephalitis virus. It infects ~50–200 million people ...
- Amudhan Murugesan, Mythreyee Manoharan
- 2020
- 10.1016/B978-0-12-819400-3.00016-8
Aug 30, 2013 · Dengue virus virulence. ADE has dominated as the explanatory model for severe dengue disease in secondary infections. However, evidence for ADE in humans is indirect and controversial results against ADE exist (112, 114). Many parts of the world have become hyperendemic, implying that all four serotypes of DENV co-circulate in the same country ...
- Anne Tuiskunen Bäck, Åke Lundkvist
- 10.3402/iee.v3i0.19839
- 2013
- 2013
Oct 1, 2023 · Dengue virus is a single-strand positive-sense RNA genome consisting of 11 kb in length [9].The single predictable polyprotein is translated by the genome that is used by the virus-encoded protein into seven non-structural proteins and three structural proteins, which are defined as follows: Non-structural gene 1 (NS1) Nonstructural gene 2 A (NS2A) and Nonstructural gene 2B (NS2b) Non ...
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes ...
