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  2. Sep 15, 2015 · Based on my clinical experience and clinical research, I recommend that papaya leave extract to be given from the first day of Dengue fever concurrently with the usual dengue management. This will reduce morbidity and mortality. Guidelines in using carica papaya leaf extract for Dengue fever patients. 1.

  3. Oct 14, 2022 · In this study, we identified three potential anti-viral compounds (Quercetin, Kaempferol, and Chlorogenic acid) from papaya leaf extracts against the dengue virus. As evidenced by the results of classical docking, MD simulations, ADME, and interaction analysis, our final compounds show inhibitory potential for the NS3 and NS5 proteins in DENV2.

    • 10.3390/ijms232012310
    • 2022/10
    • Int J Mol Sci. 2022 Oct; 23(20): 12310.
  4. Apr 26, 2021 · However, papaya leaves have been traditionally used for the treatment of dengue fever and proven effective in improving thrombocytopenia in in vitro and in vivo models although the possible mechanism behind this potential is not specified (Dengue and severe dengue, 2019).

    • Md. Moklesur Rahman Sarker, Farzana Khan, Isa Naina Mohamed
    • 2021
  5. Apr 11, 2022 · Other than larvicidal activity, this review also reveals two medicinal potentials of C. papaya leaf juice on dengue infection, namely anti-thrombocytopenic and immunomodulatory effects. C. papaya leaf juice has the potential to be a new drug candidate against dengue disease safely and effectively.

    • 10.3390/nu14081584
    • 2022/04
    • Nutrients. 2022 Apr; 14(8): 1584.
  6. Mar 29, 2017 · Mar 30, 2017. While around half the population of the world is thought to be vulnerable to dengue annually, 1 there is still no specific remedy or cure for this viral infection. But alternative medicine has long used papaya leaves for dengue, and modern research seems to be catching up.

  7. May 29, 2023 · The good news is, several local plants could potentially improve dengue signs and symptoms, including tawa tawa and neem tree2. Interestingly, some reports said that papaya leaves might also be helpful for dengue management. Here’s what you need to know about papaya leaves for dengue.

  8. Oct 14, 2022 · For centuries, papaya (Carica papaya) extracts have been traditionally used to treat DF, DHF, and DSS. In the present study, we systematically investigated seven compounds isolated from papaya leaf extract with regard to their potential as inhibitors for non-structural (NS) proteins, NS3 and NS5, which play a crucial role in viral RNA replication.

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