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  1. 5 days ago · Sepsis: Dysregulated systemic inflammatory and immune response to microbial infection that produces organ injury. Mortality Rate: 15-25%. Septic Shock: Sepsis with hyperlactatemia and concurrent hypotension requiring vasopressor therapy. Mortality Rate: 30-50%. Pathophysiology of Sepsis and Septic Shock. Sepsis has a very complex biochemical ...

  2. 4 days ago · Sepsis. Sepsis is a severe illness characterized by a systemic, whole-body response to infection and is a frequent cause of morbidity and mortality in hospitalized patients. Sepsis is most common in older individuals and infants, and can be difficult to diagnose due to its variable presentation. Because there is no confirmatory diagnostic test ...

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  4. 4 days ago · Sepsis Trust decision support tools. The following resources are based upon the NICE Sepsis Guidance CG51. GP Paediatric Sepsis Decision Support Tool (Under 5) GP Paediatric Sepsis Decision Support Tool (Aged 5-11) GP toolkit for Adults and young people aged 12 and over. Other resources including advice on pregnancy and OOH triage can also be ...

  5. 2 days ago · Nearly a third of all in-hospital deaths in 2021 were attributed to sepsis, highlighting the urgent need for improved prevention and treatment strategies. Digging deeper into the report reveals even more troubling insights. The number of sepsis-related inpatient stays surged by 20.1 percent to 2.1 million between 2016 and 2021.

  6. 5 days ago · Khan, N. et al. Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis. Sci. Transl Med. 16, eadg5768 (2024) Article PubMed Google Scholar

  7. 4 days ago · Even if the patient receives intensive care treatment, sepsis can be fatal in 30 to 50% of all cases. Some studies have also reported a mortality rate of more than 50% in the case of septic shock.

  8. 4 days ago · The goal of this activity is that learners will be better able to make a timely and accurate diagnosis for patients with pneumonia or sepsis. Upon completion of this activity, participants will: Explore the role of multiplex panel testing in the management of critical care patients

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