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Uncommon
- It is uncommon for adults to contract this disease as most people have had it by kindergarten, and once contracted, immunity arises and prevents future reinfection.
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What is human herpesvirus 6 (HHV-6)?
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Sep 8, 2022 · CLINICAL MANIFESTATIONS. Immunocompetent hosts — HHV-6 infections usually occur during childhood and result in generally mild, self-limited illnesses. Possible disease associations with HHV-6 in immunocompetent adults are not proven other than a few cases of primary infection.
Aug 8, 2023 · HHV-6B primarily infects infants and is the leading cause of virus reactivation in both, immunocompetent and immunocompromised hosts. [1] In the general population, the vast majority of adults with chronic HHV-6 remain asymptomatic. Research of HHV-6 and its role in the central nervous system is ongoing.
- Orinthia King, Yasir Al Khalili
- Virginia Commonwealth University
- 2019
- 2023/08/08
The virus periodically re-activates from its latent state, with HHV-6 DNA being detectable in 20–25% of healthy adults in the United States. In the immunocompetent setting, these re-activations are often asymptomatic, but in immunosuppressed individuals there can be serious complications.
Infection in adults is seen primarily in immunocompromised hosts with solid organ transplants or in those with human immunodeficiency virus infection. The virus is capable of pronounced interaction in vitro with cytomegalovirus and human immunodeficiency virus and induces immunosuppression and apoptosis.
- David H. Dockrell, Thomas F. Smith, Carlos V. Paya
- 1999
Dec 20, 2021 · 12 Like all strains of human herpesvirus, HHV-6 causes a primary infection, such as roseola infantum, and then stays latent in the body, where it can be reactivated by stress or other illness. 10 In some adults who experience a primary infection of HHV-6, a mononucleosis-like condition can develop.
Practice Essentials. Human herpesvirus 6 (HHV-6) is a herpesvirus that causes roseola infantum (or exanthema subitum [sixth disease]) in infants and children. [ 1] ....
Feb 27, 1996 · HHV-6 and HHV-7 are ubiquitous, and more than 90% of adults have antibody to both viruses. These viruses have extensive homology and belong to the β-herpesvirus subfamily. The genome of HHV-6A is 159 321 bp in size, has a base composition of 43% G + C, and contains 119 open reading frames.
