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  1. Lyme disease is a bacterial infection. It often causes a rash and can also cause mild symptoms that include fever, headache, and fatigue, which can be treated with a short course of antibiotics. But Lyme disease can become serious, especially if not treated early. The condition is named for Lyme, Connecticut, where a cluster of cases was first ...

  2. Most patients have a history of tick bite. Some of them may recall a rash consistent with erythema migrans some months or years earlier, often affecting the same limb. Erythema migrans is a ring-like rash that occurs around the site of a Borrelia-infected tick bite. [see Erythema migrans images] Clinical features of acrodermatitis chronica ...

  3. Signs and symptoms of the second stage of Lyme disease (the early disseminated stage) may include: Multiple areas of rash. Paralysis of facial muscles ( Bell's palsy ). Heart block or an interruption of the electrical system of the heart. Areas of numbness or abnormal feelings ( neuropathy ).

  4. Early Localized (3 to 30 days after a tick bite): Erythema migrans (EM)— Red annular or homogeneous rash at the site of tick bite; expands gradually over several days to >5 cm in diameter; central clearing may develop as the rash expands, resulting in a “target” or “bull’s-eye” appearance; may feel warm to the touch but rarely itchy or painful.

  5. Mar 31, 2023 · Thirty percent or more of people with Lyme disease don’t remember having the rash . Even fewer people remember a tick attachment. Estimates range from 20 to 50 percent ( 10 ).

  6. Feb 14, 2018 · The rash isn’t a disease in itself. Rather, it can be a symptom of an underlying condition, such as: ... Rarely, erythema marginatum can be one of the skin symptoms of Lyme disease, though ...

  7. Sep 20, 2021 · During stage 2, the rash will take roughly one to six months to appear. It will be markedly different from stage 1 and appear as small oval-shaped rashes, typically appearing on various parts of the body such as the face, legs, and arms. The center of a stage 2 Lyme disease rash may also be darker in the center or appear bluish with a clear center.

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