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  1. Osler nodes and Janeway lesions are two rare but well-known skin manifestations of bacterial endocarditis. They have also rarely been described in systemic lupus erythematosus (SLE), gonococcaemia ( gonorrhoea ), haemolytic anaemia and typhoid fever. They are important as they may help in the earlier diagnosis of a serious medical disorder.

  2. Nov 17, 2022 · Janeway lesions are skin patches that develop on the palms and feet. They usually indicate infective endocarditis. Infective endocarditis causes inflammation in the heart valves or lining. It results when bacteria, such as staphylococcus aureus, enter the bloodstream and settle in the heart lining. Janeway lesions commonly occur with Osler’s ...

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  4. Janeway lesions on the sole of the foot (A) and palm of the hand (B). Fig 2. Echocardiogram showing endocarditis vegetation. Janeway lesions are painless, macular, haemorrhagic lesions that occur most commonly on the palmar surface of the hands and feet.

    • Andrea Misin, Stefano Di Bella, Luigi Priolo, Roberto Luzzati
    • 10.7861/clinmedicine.17-4-373
    • 2017
    • Clin Med (Lond). 2017 Aug; 17(4): 373-374.
  5. Infective Endocarditis (Osler Node and Janeway Lesions) The image on the left shows an Osler node (tender and erythematous nodule) on the thumb. The image on the right shows Janeway lesions (nontender and erythematous macules on the palm). © Springer Science+Business Media. In these topics.

  6. Jul 24, 2023 · Identification of Osler nodes and Janeway lesions may aid in diagnosing the underlying condition, often infective endocarditis. As per the modified Duke criteria, cutaneous manifestations are minor supporting criteria for infective endocarditis.

    • Krishan Parashar, Steven Daveluy
    • 2023/07/24
    • 2021
  7. This patient with infective endocarditis has multiple Janeway lesions (nontender, erythematous papules) on the palms. The patient also has some Osler nodes (tender, erythematous nodules on the fingers).

  8. This patient with infective endocarditis has multiple Janeway lesions (nontender, erythematous papules) on the palms. The patient also has some Osler nodes (tender, erythematous nodules on the fingers).

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