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Jul 2, 2023 · Erythromycin is a bacteriostatic antibiotic, which means it prevents the further growth of bacteria rather than directly destroying them. This action occurs by inhibiting protein synthesis. Erythromycin binds to the 23S ribosomal RNA molecule in the 50S subunit of the bacterial ribosome; this causes a blockage in peptide chain synthesis ...
- 2023/07/02
Aug 14, 2023 · [7] [8] Erythromycin has poor activity against gram-negative and anaerobic organisms. However, it is extremely effective against atypical pathogens and has some activity against Neisseria spp. Clarithromycin has a similar spectrum of activity to erythromycin, with additional activity against some staph and strep species.
- John Loree, Sarah L. Lappin
- 2023/08/14
- Upstate University Hospital
Erythromycin can be used to treat bacteria responsible for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera. The following represents MIC susceptibility data for a few medically significant bacteria: [12] Haemophilus influenzae: 0.015 to 256 μg/ml.
- C₃₇H₆₇NO₁₃
- AU: A
- liver (under 5% excreted unchanged)
- Eryc, Erythrocin, others
Sep 28, 2014 · The categorization of antibiotics into bacteriostatic and bactericidal is unlikely to be relevant in clinical practice if used for abdominal infections, skin and soft tissue infections and pneumonia. Because we were not able to include studies on meningitis, endocarditis or neutropenia, no conclusion regarding these diseases can be drawn.
- Johannes Nemeth, Gabriela Oesch, Stefan P. Kuster
- 2015
May 1, 2018 · The PubMed database was searched using the following terms for commonly used bacteriostatic agents: “azithromycin” OR “chloramphenicol” OR “clarithromycin” OR “clindamycin” OR “doxycycline” OR “linezolid” OR “erythromycin” OR “tetracycline” OR “tigecycline” OR “eravacycline.”
- Noah Wald-Dickler, Paul Holtom, Brad Spellberg
- 2018
May 4, 2022 · Overview of Antibacterial Drugs. By. Brian J. Werth. , PharmD, University of Washington School of Pharmacy. Reviewed/Revised May 2022. View PATIENT EDUCATION. Selection and Use of Antibiotics. Antibiotic Resistance. Antibacterial drugs are derived from bacteria or molds or are synthesized de novo.
Erythromycin is active against most gram-positive bacteria; some gram-negative bacteria, including Neisseria, Bordetella, Brucella, Campylobacter, and Legionella; and Treponema, Chlamydia, and Mycoplasma. The emergence of resistance to erythromycin is closely associated with its use and is often plasmid mediated.