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Jul 2, 2023 · Erythromycin is a bacteriostatic antibiotic, which means it prevents the further growth of bacteria rather than directly destroying them. This action occurs by inhibiting protein synthesis. Erythromycin binds to the 23S ribosomal RNA molecule in the 50S subunit of the bacterial ribosome; this causes a blockage in peptide chain synthesis ...
- Bacteriostatic Antibiotics - StatPearls - NCBI Bookshelf
The term "bacteriostatic antibiotics" is used to describe...
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- Bacteriostatic Antibiotics - StatPearls - NCBI Bookshelf
Erythromycin is a macrolide that acts by inhibiting the translocation reaction during protein synthesis. Erythromycin is inactive against the Enterobacteriaceae and Pseudomonas aeruginosa except under alkaline conditions. Erythromycin is active against most gram-positive bacteria; some gram-negative bacteria, including Neisseria, Bordetella, Brucella, Campylobacter, and Legionella; and ...
- John A. Washington, Walter R. Wilson
- 1985
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Dec 27, 2017 · The formal definition of a bactericidal antibiotic is one for which the ratio of MBC to MIC is ≤ 4, while a bacteriostatic agent has an MBC to MIC ratio of > 4. Thus, an antibiotic that achieves a >1,000-fold reduction in bacterial density but does so at a concentration that is 8-fold above the MIC of the drug is considered bacteriostatic ...
Erythromycin, first introduced for clinical use 30 years ago, was found to be effective for the treatment of gram-positive bacterial infections. Emergence of resistance and the advent of penicillinase-resistant penicillins limited the use of erythromycin for serious staphylococcal infections; however, erythromycin remains among the drugs of choice for the treatment of acne, infections of the ...
- John A. Washington, Walter R. Wilson
- 1985
May 4, 2022 · Technically, “antibiotic” refers only to antimicrobials derived from bacteria or molds but is often (including in THE MANUAL) used synonymously with “antibacterial drug.”. (See also Antibiotics in Neonates.) Antibiotics have many mechanisms of action, including the following: Inhibiting cell wall synthesis. Increasing cell membrane ...
