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- Pediatric consensus definitions for sepsis are not accurate in term infants and are not appropriate for preterm infants.
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Oct 1, 2021 · Very preterm infants with EOS died at higher rates, and survivors had significantly increased risk of morbidities compared with uninfected infants. The profoundly negative impact of EOS on very preterm infants highlights the need for novel preventive strategies among such infants.
- Dustin D. Flannery, Dustin D. Flannery, Erika M. Edwards, Karen M. Puopolo, Karen M. Puopolo, Jeffre...
- 2021
Pediatric sepsis criteria are not accurate for term neonates and have not been examined in preterm neonates for whom the developmental stage influences aberrations associated with host immune response.
- James L. Wynn, Hector R. Wong, Hector R. Wong, Thomas P. Shanley, Matthew J. Bizzarro, Lisa Saiman, ...
- 2014
Pediatric consensus definitions for sepsis are not accurate for term neonates and were not designed for preterm neonates. The development and acceptance of a consensus definition for neonatal sepsis is an important and necessary step towards the goal of improving outcomes.
- James L. Wynn
- 2016
Mar 19, 2020 · There are major differences between a baby arriving to the emergency room with a fever in the first month of life compared to a preterm infant born following severe chorioamnionitis and...
- Eleanor J. Molloy, James L. Wynn, Joseph Bliss, Joyce M. Koenig, Fleur M. Keij, Matt McGovern, Helmu...
- 2020
Nov 11, 2022 · Late-onset sepsis was defined as isolation of a pathogenic bacteria from blood and/or cerebrospinal fluid, or fungi from blood, obtained >3 days after birth. Demographics, clinical characteristics, and outcomes were compared between infants with and without late-onset sepsis. RESULTS.
Jun 9, 2020 · Early-onset sepsis (EOS) remains a significant cause of morbidity and mortality among newborns, particularly preterm infants, and requires ongoing surveillance for identification of changes in etiologic agents and antimicrobial resistance, according to study results published in JAMA Pediatrics. 1
Diagnosis. Prognosis. Treatment. Sepsis is a serious bodywide reaction to infection spread through the blood. Newborns with sepsis appear generally ill—they are listless, do not feed well, often have a gray color, and may have a fever or a low body temperature. The diagnosis is based on the symptoms and the presence of bacteria. , a virus.
