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  1. Aug 13, 2022 · Critical Appraisal of the Literature. To evaluate clinically relevant articles regarding the diagnosis and early management of sepsis, severe sepsis, and septic shock, a search of the National Library of Medicine PubMed database was performed using the following search terms: sepsis management, septic shock management, and clinical sepsis treatment guidelines, with a date range of 2000 to 2018.

  2. May 04, 2021 · This Consensus Statement outlines a definition for the term ‘postbiotics’ as determined by an expert panel convened by the International Scientific Association for Probiotics and Prebiotics.

  3. Neonatal thrombocytopenia is a common clinical problem. Thrombocytopenia presenting in the first 72 hours of life is usually secondary to placental insufficiency and caused by reduced platelet production; fortunately most episodes are mild or moderate and resolve spontaneously. Thrombocytopenia presenting after 72 hours of age is usually secondary to sepsis or necrotising enterocolitis and is ...

  4. Nov 12, 2019 · Sepsis is one of the most important causes of maternal death in the UK, 3 and there is an 8% risk of mortality across HICs. 4, 5 Morbidity, not insignificant in survivors, has an estimated morbidity/mortality ratio of 50:1. 6 The World Health Organization (WHO) reports the prevalence of puerperal sepsis alone in live births as 4.4% (equating to ...

  5. Some infants and children may have ProCT levels from 0.15 ng/mL to 0.50 ng/mL for unknown reasons. As with all immunometric assays, there is a low, but definite possibility of false-positive results in patients with heterophile antibodies. Test results that do not fit the clinical picture should therefore be discussed with the laboratory.

  6. Jul 30, 2022 · Background We aimed to explore the prognostic utilities of C-reactive protein (CRP), procalcitonin (PCT), neutrophil CD64 (nCD64) index, in combination or alone, in septic patients. Methods We retrospectively included 349 septic patients (based on Sepsis 3.0 definition). The primary outcome was 28-day all-cause mortality. Cox regression model, receiver-operating characteristic (ROC) curve ...

  7. A wide range of signs and symptoms can be experienced in patients at various stages of sepsis development. While infections can potentially trigger sepsis development in everyone, a number of groups are at increased risk including Aboriginal and Torres Strait Islander people, neonates, paediatrics, pregnant and post-partum women, the elderly, patients with chronic and complex disease and ...