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  1. Jul 10, 2019 · West Nile virus (WNV) is a single-stranded RNA virus which belongs to the family Flaviviridae, genus Flavivirus. This family includes several important human arthropod-borne pathogens, such as dengue (DENV), Zika (ZIKV), tick-borne encephalitis (TBEV), Yellow fever (YFV) or Japanese encephalitis (JEV) viruses. 1 WNV circulates in birds and is ...

    • PMC Free Article

      Forty-three of 45 monkeys vaccinated with 10 2.3 or greater...

  2. Jan 31, 2024 · In 2019, the four serotypes of the mosquito-borne dengue virus (DENV) caused an estimated 56 million cases of disease and 5000 to 40,000 deaths in a global swath of tropical and near-tropical...

  3. Apr 29, 2023 · Several factors have hindered WNV vaccines from moving forward into later stages of clinical development, including challenges with designing and implementing efficacy studies, potential...

  4. Oct 6, 2022 · Oct. 6, 2022. Sarah Leach at a microscope in the closed-door section of the lab where the team works with live zika, West Nile, and other viruses, to find commonalities and ultimately, lead the way for new vaccines. Photos by Cyrus McCrimmon, for UCHealth.

  5. Apr 29, 2023 · Combating Wes N l V rus D a. It is time to revisit the need for human West Nile virus (WNV) vaccines. Since its initial detection in the United States in 1999, WNV has become the leading cause of ...

  6. Dec 21, 2020 · Among the main targets of viral vaccination are (re) emerging pathogens that have caused recent epidemics/pandemics around the world, such as avian influenza, Ebola, SARS, MERS, Chikungunya, Zika, Dengue, and West Nile viruses, as well as those that may pose a threat in the future.

  7. Besides WNV, there are several clinically significant human pathogens within this group including St. Louis encephalitis virus (SLEV), dengue virus (DENV), tick-borne encephalitis virus (TBEV), Japanese encephalitis virus (JEV), Murray Valley encephalitis virus (MVEV), and yellow fever virus (YFV) [1,2]. These single-stranded positive-sense RNA ...