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Janeway lesions are one of the stigmata of infectious endocarditis. They are irregular, erythematous, flat, painless macules on the palms, soles, thenar and hypothenar eminences of the hands, tips of the fingers, and plantar surfaces of the toes; they rarely present as a diffuse rash, and are very rare in clinical practice.
Janeway lesions are small, painless hemorrhages with a macular or slightly nodular character ( Fig. 62.5 ). They are found on the thenar and hypothenar eminences of the palms and soles. The histologic findings are generally consistent with septic microemboli. Bacteria have been cultured from these lesions.
Apr 19, 2017 · Janeway lesions are erythematous or hemorrhagic macular non-tender lesions on palms and soles and are the consequence of septic embolic events. 1 Lesions on histopathological evaluation show necrotic microabscesses. 2 Previously, seen in 6–10% of the patients with endocarditis, the occurrence in the present era is rare due to early initiation of...
