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  1. Apr 18, 2019 · Janeway lesions are nontender hemorrhagic macules or papules located on palms, soles, and thenar and hypothenar eminences. Osler’s nodes are painful violaceous nodes typically found on fingers and toes. Traditionally, Janeway lesions have been attributed to septic emboli and Osler’s nodes described as an immunologic phenomenon.

  2. Feb 19, 2013 · Janeway lesions are named after Theodore Caldwell Janeway (1872–1917), an American professor of medicine. They are nontender, erythematous or hemorrhagic macular or nodular lesions on the palms or soles. 1 They are commonly seen in acute endocarditis.

  3. Jul 7, 2010 · Janeway lesions are irregular, nontender hemorrhagic macules located on the palms, soles, thenar and hypothenar eminences of the hands, and plantar surfaces of the toes. They typically last for days to weeks. They are usually seen with the acute form of bacterial endocarditis.

  4. Jan 16, 2021 · Janeway lesions are irregular, painless, erythematous or haemorrhagic macules, or papules commonly found on the palms and soles. The pathogenesis of Janeway lesions is still a controversial topic in the literature, but the main hypothesis is based on septic embolic events.

  5. Janeway lesions are one of the stigmata of infectious endocarditis. They are irregular, erythematous, flat, painless macules on the palms, soles, thenar and hypothenar eminences of the hands, tips of the fingers, and plantar surfaces of the toes; they rarely present as a diffuse rash, and are very rare in clinical practice.

  6. Janeway lesions are small, painless hemorrhages with a macular or slightly nodular character ( Fig. 62.5 ). They are found on the thenar and hypothenar eminences of the palms and soles. The histologic findings are generally consistent with septic microemboli. Bacteria have been cultured from these lesions.

  7. Apr 19, 2017 · Janeway lesions are erythematous or hemorrhagic macular non-tender lesions on palms and soles and are the consequence of septic embolic events. 1 Lesions on histopathological evaluation show necrotic microabscesses. 2 Previously, seen in 6–10% of the patients with endocarditis, the occurrence in the present era is rare due to early initiation of...

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