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Osler nodes and Janeway lesions are two rare but well-known skin manifestations of bacterial endocarditis. They have also rarely been described in systemic lupus erythematosus (SLE), gonococcaemia ( gonorrhoea ), haemolytic anaemia and typhoid fever. They are important as they may help in the earlier diagnosis of a serious medical disorder.
Jul 24, 2023 · Osler nodes and Janeway lesions are cutaneous manifestations of endocarditis, a disease most commonly arising from a bacterial or fungal infection of the cardiac endocardium.[1] Osler nodes are tender, purple-pink nodules with a pale center and an average diameter of 1 to 1.5 mm.[2] They are generally found on the distal fingers and toes, though they can also present on the lateral digits ...
- Krishan Parashar, Steven Daveluy
- 2023/07/24
- 2021
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Jun 5, 2022 · Janeway lesions in a 15-year-old adolescent with aortic valve infective endocarditis: hemorrhagic macules of the palms and soles that are due to septic emboli. In newborn children, the manifestations of IE are nonspecific and can be confused with other more common systemic infections, such as pneumonia or urinary tract infections.
- 10.3390/jcm11113217
- 2022/06
- J Clin Med. 2022 Jun; 11(11): 3217.
Epidemiology and Clinical Findings of IE in Children. In a previous report, IE occurred less often in children than in adults and accounted for approximately 1 in 1280 (0.78 per 1000) pediatric admissions per year from 1972 to 1982 at a referral insitution. 4 In a recent multicenter report, 5 the annual incidence rate in the United States was between approximately 0.05 and 0.12 cases per 1000 ...
- Robert S. Baltimore, Michael Gewitz, Larry M. Baddour, Lee B. Beerman, Mary Anne Jackson, Peter B. L...
- 2015
Apr 25, 2016 · Embolic events are known clinical stigmata of infective endocarditis occurring in 20 to 50% of cases and are often associated with protracted bacteremia. Janeway lesions are an example of this embolic phenomenon and can be a silent clinical sign ( 1 ). In cases where patients are incapacitated to a point where history acquisition becomes ...
- Shoaib Bilal Fareedy, Priya Rajagopalan, Espana Christian Schmidt
- 10.3402/jchimp.v6.30660
- 2016
- 2016
Jun 5, 2022 · Figure 1. Janeway lesions in a 15-year-old adolescent with aortic valve infective endocarditis: hem-orrhagic macules of the palms and soles that are due to septic emboli. In newborn children, the manifestations of IE are nonspecific and can be confused with other more common systemic infections, such as pneumonia or urinary tract infec-tions.
Jun 15, 2020 · Janeway lesions, Osler’s nodes and splinter hemorrhages are the classical signs of IE previously described in the literature. It was commonly seen in cases of IE in pre-antibiotic era and its only present in 3–5% of cases at present. 3 Janeway lesions are irregular, non-tender, hemorrhagic macules typically located on the palm and soles of ...
