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  1. In contrast to Osler nodes, Janeway lesions are non-tender, often haemorrhagic (bleeding into the skin), and occur mostly on the palms and soles on the thenar and hypothenar eminences (at the base of the thumb and little finger respectively). They tend to last days to weeks before healing totally.

  2. Jul 24, 2023 · As per the modified Duke criteria, Osler nodes are considered immunologic phenomena of infective endocarditis, and Janeway lesions, vascular phenomena. Osler nodes more commonly correlate with subacute endocarditis, whereas Janeway lesions typically occur in acute infective endocarditis.

  3. Janeway Lesions vs. Osler Nodes. Both found in bacterial endocarditis. Osler Nodes: Painful, palpable red lesions usually on fingers/toes. They are caused by immune complexes. (Image Credit) Janeway Lesions; Non-painful, macular lesions, usually on palms/soles. They are caused by septic emboli, more common in Staph aureus endocarditis. (Image ...

  4. Janeway's lesions and Osler's nodes are highly prized clues to the diagnosis of infectious endocarditis that are often searched for but seldom found. Only a relatively few physicians have actually seen an Osler's node, and even fewer can clearly distinguish an Osler's node from a Janeway's lesion.

  5. Janeway lesions are painless, macular, haemorrhagic lesions that occur most commonly on the palmar surface of the hands and feet. These lesions are non-tender, in contrast to the exquisitely painful Oslers node.

  6. Apr 18, 2019 · Janeway lesions and Oslers nodes are both classic stigmata of endocarditis, but distinguishing the two can be difficult. Janeway lesions are nontender hemorrhagic macules or papules located on palms, soles, and thenar and hypothenar eminences. Oslers nodes are painful violaceous nodes typically found on fingers and toes.

  7. Jul 24, 2023 · Osler nodes and Janeway lesions are cutaneous manifestations of endocarditis, a disease most commonly arising from a bacterial or fungal infection of the cardiac endocardium. Osler nodes are tender, purple-pink nodules with a pale center and an average diameter of 1 to 1.5 mm.

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