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Osler nodes and Janeway lesions are two rare but well-known skin manifestations of bacterial endocarditis. They have also rarely been described in systemic lupus erythematosus (SLE), gonococcaemia ( gonorrhoea ), haemolytic anaemia and typhoid fever. They are important as they may help in the earlier diagnosis of a serious medical disorder.
Jul 24, 2023 · Osler nodes and Janeway lesions are cutaneous manifestations of endocarditis, a disease most commonly arising from a bacterial or fungal infection of the cardiac endocardium.[1] Osler nodes are tender, purple-pink nodules with a pale center and an average diameter of 1 to 1.5 mm.[2] They are generally found on the distal fingers and toes, though they can also present on the lateral digits ...
- Krishan Parashar, Steven Daveluy
- 2023/07/24
- 2021
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Nov 17, 2022 · Most cases of Janeway lesions occur with Trusted Source American Journal of Clinical Nutrition Peer reviewed journal Go to source Osler’s nodes. Osler’s nodes are tender red-to-purple lumps that form on the fingers or toes. Read on to learn more about Janeway lesions, including their causes, symptoms, and treatment.
Janeway Lesions vs. Osler Nodes. Both found in bacterial endocarditis. Osler Nodes: Painful, palpable red lesions usually on fingers/toes. They are caused by immune complexes. (Image Credit) Janeway Lesions; Non-painful, macular lesions, usually on palms/soles. They are caused by septic emboli, more common in Staph aureus endocarditis. (Image ...
Fig 1. Janeway lesions on the sole of the foot (A) and palm of the hand (B). Fig 2. Echocardiogram showing endocarditis vegetation. Janeway lesions are painless, macular, haemorrhagic lesions that occur most commonly on the palmar surface of the hands and feet. These lesions are non-tender, in contrast to the exquisitely painful Osler’s node.
- Andrea Misin, Stefano Di Bella, Luigi Priolo, Roberto Luzzati
- 10.7861/clinmedicine.17-4-373
- 2017
- Clin Med (Lond). 2017 Aug; 17(4): 373-374.
May 12, 2015 · The main IE dermatologic manifestations are Osler’s nodes and Janeway lesions. Such rare signs are found only in 5-15% of IE patients. The prevalence rates may be underestimated due to the lack of a systematic approach to dermatological examination in IE patients. 5, 6. The pathogenesis of Osler’s nodes and Janeway lesions remains ...
The image on the left shows an Osler node (tender and erythematous nodule) on the thumb. The image on the right shows Janeway lesions (nontender and erythematous macules on the palm).
