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  1. May 22, 2023 · Summarize the pathophysiology of type III hypersensitivity reaction. Explain the management of type III hypersensitivity reaction. Review the interprofessional team strategies that can enhance patient outcomes.

    • Norina Usman, Pavan Annamaraju
    • 2023/05/22
    • 2021
  2. Oct 30, 2023 · Drug hypersensitivity reactions (DHR) include allergic, exaggerated pharmacologic, and pseudoallergic reactions to medications that result from an enhanced immunologic or inflammatory response.

  3. May 9, 2015 · Drug hypersensitivity reactions are unpredictable adverse drug reactions. They manifest either within 1–6 h following drug intake (immediate reactions) with mild to life-threatening symptoms of anaphylaxis, or several hours to days later (delayed reactions), primarily as exanthematous eruptions.

    • 10.1007/s40629-015-0052-6
    • 2015
    • Allergo J Int. 2015; 24(3): 94-105.
  4. Type III: Immune complex deposition reactions with activation of complement, such as serum sickness–like reactions (SSLRs). Type IV : Delayed T-lymphocyte-mediated reactions, such as contact dermatitis and delayed maculopapular rashes.

    • Ana Dioun Broyles, Aleena Banerji, Mariana Castells
    • 2020
  5. Type III hypersensitivity, in the Gell and Coombs classification of allergic reactions, occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes.

  6. Dec 20, 2023 · Serum sickness (SS) is a type III hypersensitivity reaction that is induced by administration of foreign proteins, classically horse serum containing diphtheria antitoxin, and has been associated with antibiotics, biologics, vaccines and venoms. 1-3 The onset of SS is classically delayed, up to 1 to 3 weeks from exposure, and symptoms include fe...

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  8. Dec 3, 2021 · Type III hypersensitivity. Type III hypersensitivity is an antigen-antibody immune complex-mediated reaction, which can occur over hours, days or weeks. Examples include serum sickness, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and post-streptococcal glomerulonephritis.

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