Search results
Anthony J. Covarrubias, PH.D. Assistant Professor. AJCovarrubias@mednet.ucla.edu. (310) 794-5683. 650 Charles E Young Dr, CHS 27-200H, Los Angeles, CA, 90095. Lab Website: www.CovarrubiasLab.com. Affiliations: MIMG, MBI, Metabolism Theme Space, Immunology Theme Space (I3T), and CTSI.
John Covarrubias - TV Writer/Producer - Prime Video & Amazon Studios | LinkedIn. TV Writer/Producer. Los Angeles Metropolitan Area. 331 followers 332 connections. View mutual connections with...
- 331
- Prime Video & Amazon Studios, Starz
- TV Writer/Producer
- Los Angeles Metropolitan Area
John grew up in Los Angeles and received his MFA in Directing from the UCLA School of Film, Television and Digital Media. He began his television career as a freelance editor and then as a producer/editor for CBS, creating original video content for the broadcast company’s interactive division.
- A Tune-Up For Mitochondria
- Slowing Aging with Α-Ketoglutarate
- The Future of Mitochondria and Aging
Researchers suspect that super-efficient mitochondria age their hosts much more gracefully. Huang reasoned that because metabolism helps control aging, compounds produced in cells by metabolic reactions, known as metabolites, might be manipulated to prolong life. To conduct her research, Huang and her lab invented a new technology, Drug Affinity Re...
α-KG is an important biological molecule involved in the Krebs cycle, the chemical reactions involved in a cell’s production of energy. Huang’s team found that α-KG can slow aging because α-KG binds to ATP synthase in the cell’s mitochondria. ATP synthase is the heart of the Krebs cycle. It is the machinery in the membrane of mitochondria that gene...
Huang has already found other metabolites that inhibit ATP production, most of which are easier to use than α-KG. Giving mice these drugs in water also inhibited production of cataracts and prevented hair loss. She also has found a different metabolite, 2-HG, that cuts energy use in glioblastoma, the most virulent of brain cancers. Future research ...
Covarrubias Lab. UCLA David Geffen School of Medicine and Life Sciences. Los Angeles, CA 90095 | (310) 794-5837 |
5 days ago · Tumor Immunology & Immunotherapy. The UCLA Health Jonsson Comprehensive Cancer Center Tumor Immunology & Immunotherapy (TII) research program provides a research environment focused on enhancing the understanding of tumor immunology and developing new immunotherapies for cancer.
Covarrubias Lab. Located at the UCLA David Geffen School of Medicine, Department of Microbiology, Immunology, and Molecular Genetics, UCLA Metabolism and Immunology Theme Space. Exploring the forefront of immuno-metabolism, inflammation, and chronic diseases. We explore.
