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Learn about the etiology, clinical features, diagnosis, treatment, and prevention of acute rheumatic fever, a delayed sequela of group A strep infections. The web page explains the Jones Criteria, a clinical diagnosis tool based on major and minor manifestations of the disease.
Apr 29, 2020 · A calculator that diagnoses acute rheumatic fever based on presence of major and minor criteria in pediatric patients with preceding GAS infection. The criteria include evidence of preceding GAS infection, carditis, arthritis, chorea, erythema marginatum, subcutaneous nodules, fever, sedimentation rate, C-reactive protein and PR interval. The calculator also distinguishes between low-risk and high-risk populations.
- Rationale: Although the incidence of acute rheumatic fever (ARF) has declined in Europe and North America over the past 4-6 decades, the disease remains one of the most important causes of cardiovascular morbidity and mortality among socially and economically disadvantaged populations all over the world, especially in developing countries that are home to the majority of the world’s population.
- Epidemiology: The global distribution of ARF and RHD is heterogeneous; certain geographic regions and specific ethnic and socioeconomic groups experience very high rates of ARF, whereas the disease has virtually disappeared in other regions.
- Epidemiologic implications: It is reasonable to consider individuals at low risk of ARF if they come from a setting or population with known low rates of ARF and RHD (Class IIa, Level of Evidence C).
- Clinical manifestations of ARF: The major clinical manifestations of ARF are carditis and arthritis, followed in descending frequency by chorea (with a female predominance), subcutaneous nodules, and erhythema marginatum (uncommon but specific of ARF).
Aug 2, 2023 · The diagnosis of a recurrent episode of ARF requires 2 major criteria, 1 major and 2 minor criteria, or 3 minor criteria (see Table 1). [45] A presumptive diagnosis of ARF may be made without using the Jones Criteria in patients presenting with SC or indolent carditis months after GAS infection.
- 2023/08/02
Jul 10, 2020 · Learn about rheumatic fever, a systemic inflammatory disorder that arises as a complication of group A Streptococcus infection. Find out the clinical features, pathophysiology, risk factors and Jones criteria for diagnosis.
This revision of the Jones criteria now brings them into closer alignment with other international guidelines for the diagnosis of acute rheumatic fever by defining high-risk populations, recognizing variability in clinical presentation in these high-risk populations, and including Doppler echocardiography as a tool to diagnose cardiac involvement.
Aug 19, 2015 · The Jones criteria has longed served as the primary guideline for diagnosing acute rheumatic fever (ARF). However, since the first iteration in 1944, the global epidemiology of ARF and our knowledge regarding the variability of its presentation have changed.
