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  1. Sep 6, 2021 · In this review, we describe the potential therapeutic usages of CPPs (mainly trans-activator of transcription protein, TAT) in enabling the uptake of biologically active proteins/enzymes needed in cases of protein/enzyme deficiency, concentrating on mitochondrial diseases and on the import of enzymes or peptides in order to destroy pathogenic ce...

    • Ndufaf4

      We used the approach of cell- and organelle-directed...

  2. Development of a cell transducible RhoA inhibitor TAT-C3 transferase and its encapsulation in biocompatible microspheres to promote survival and enhance regeneration of severed neurons. Pharm Res. 2007 Dec;24 (12):2297-308. doi: 10.1007/s11095-007-9454-6. Epub 2007 Sep 25.

    • Elaine Y.M. Tan, Janice W.S. Law, Chi Hwa Wang, Alan Y.W. Lee
    • 2007
  3. Pressburg, Kingdom of Hungary, Habsburg monarchy (now Bratislava, Slovakia) Occupation (s) historian, pedagogue. Juraj Sklenár (Georgius Szklenár; 25 February 1745 – 30 January 1790) was a Slovak historian, pedagogue and Catholic priest.

    • historian, pedagogue
  4. Jun 6, 2022 · PMID: 35674133. A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model. Shalini Saggu, 1 Yunjia Chen, 1 Liping Chen, 1 Diana Pizarro, 2 Sandipan Pati, 2 Wen Jing Law, 1 Lori McMahon, 1 Kai Jiao, 3 and Qin Wang 1.

    • 10.1172/jci.insight.155002
    • 2022/06/06
    • JCI Insight. 2022 Jun 8; 7(11): e155002.
  5. Mar 6, 2001 · 707 Citations. 9 Altmetric. Metrics. Abstract. Increased phosphorylation of myosin light chain (MLC) is necessary for the dynamic membrane blebbing that is observed at the onset of apoptosis. Here...

    • Michaël Sebbagh, Claire Renvoizé, Jocelyne Hamelin, Nicole Riché, Jacques Bertoglio, Jacqueline Bréa...
    • 2001
  6. Oct 1, 2003 · Exoenzyme Tat-C3 Inhibits Association of Zymosan Particles, Phagocytosis, Adhesion, and Complement Binding in Macrophage Cells. Phagocytosis by macrophages is most important in the initial stages of an immune response. Although RhoA regulates cell adhesion, its roles in the integrin-related association of particles with macrophages and in ...

  7. Aug 27, 2012 · Interestingly, when actin-depolymerizing agents were used, including TAT-C3 transferase at 16 µg/mL (Fig. 6, line e), Y-27632 at 20 µM or 80 µM (Fig. 6, lines f and g) and Bleb at 50 µM (data not shown), stress fibers and pattern of semi-ordered cells disappeared. In these conditions, MDV plaques adopted a more rounded shape, in addition to ...

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