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  1. Nov 18, 2014 · The diagnosis of von Willebrand disease (VWD) incorporates the following three parameters: 1) a personal history of excessive mucocutaneous bleeding, 2) laboratory studies demonstrating quantitative and/or qualitative defects of von Willebrand factor (VWF), and 3) a family history of abnormal bleeding.

    • Robert Montgomery, Jonathan Roberts, Gilbert C. White Ii
    • 2014
  2. Dec 9, 2022 · Most people with von Willebrand disease (VWD) have a partial quantitative deficiency of plasma von Willebrand factor (VWF) or type 1 VWD. In contrast to type 2 and type 3 VWD, laboratory assays will not always establish the diagnosis in type 1 VWD.

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  4. Von Willebrand Disease (VWD), the most common inherited bleeding disorder, is defined by decreased activity of von Willebrand Factor (VWF) activity in the blood. This can be secondary to a quantitative or qualitative defect.

    • Angela C. Weyand, Veronica H. Flood
    • 2021/12
    • 10.1016/j.hoc.2021.07.004
  5. Apr 26, 2017 · Type 1 VWD represents the majority of cases and results from a partial quantitative deficiency of von Willebrand factor (VWF). The diagnosis of Type 1 VWD presents many challenges, despite there being three established diagnostic criteria: a personal history of mucocutaneous bleeding, a family history and low VWF levels.

    • M. L. Bowman, P. D. James
    • 2017
  6. Mar 29, 2020 · Von Willebrand disease (VWD) is a defect of the primary hemostatic pathway that results from quantitative or qualitative deficiencies of the von Willebrand factor (VWF). Type 1 VWD is the commonest form and occurs due to reduced level of VWF protein.

    • Dominder Kaur, Sarah H. O’Brien, Sarah H. O’Brien
    • 2020
  7. Von Willebrand disease is classified into 3 main types: Type 1: A quantitative deficiency of VWF, which is the most common form and is an autosomal dominant disorder. VWD concentration and activity are both reduced proportionally.

  8. Nov 29, 2018 · von willebrand disease, type 1, von willebrand factor, hemorrhage, antigens, factor viii, laboratory techniques and procedures, assessment scales, blood type, blood type o, clinical diagnosis Author notes

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