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1. www.nature.com › articles › s41580/020/0218-zThe antitumorigenic roles of BRCA1–BARD1 in DNA repair and ...

   www.nature.com › articles › s41580/020/0218-z

   Feb 24, 2020 · Abstract. The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA...

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2. www.nature.com › articles › s41598/020/65584-yPrediction of breast cancer proteins involved in ... - Nature

   www.nature.com › articles › s41598/020/65584-y

   May 22, 2020 · Regarding the prediction of 4,504 cancer-associated proteins using this model, the best ranked cancer immunotherapy proteins related to BC were RPS27, SUPT4H1, CLPSL2, POLR2K, RPL38,...

   • Author: Andrés López-Cortés, Alejandro Cabrera-Andrade, José M. Vázquez-Naya, Alejandro Pazos, Humberto Gonz...

   • Publish Year: 2020

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4. pubmed.ncbi.nlm.nih.gov › 35534113Computational structural assessment of BReast CAncer type 1 ...

   pubmed.ncbi.nlm.nih.gov › 35534113

   Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein interface. Adv Protein Chem Struct Biol. 2022;130:375-397. doi: 10.1016/bs.apcsb.2022.02.003.

5. pubmed.ncbi.nlm.nih.gov › 32094664The antitumorigenic roles of BRCA1-BARD1 in DNA ... - PubMed

   pubmed.ncbi.nlm.nih.gov › 32094664

   The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication forks from attrition. BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor proteins to mediate the initial nucleolytic ...

   • Author: Madalena Tarsounas, Patrick Sung

   • Publish Year: 2020

6. pubmed.ncbi.nlm.nih.gov › 35064849Perspectives on the role of breast cancer susceptibility gene ...

   pubmed.ncbi.nlm.nih.gov › 35064849

   The breast cancer susceptibility gene 1 protein expression was significantly correlated with family history of breast cancer patients (p = 0.006), local lymph node metastases (p = 0.001), and TNM staging (p ≤ 0.001).

7. People also ask

   What does BRCA1 do in breast cancer?

   • The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication forks from attrition. BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor protei …

   The antitumorigenic roles of BRCA1-BARD1 in DNA repair and

   pubmed.ncbi.nlm.nih.gov/32094664/

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   Is BRCA1 deficiency the most aggressive form of breast cancer?

   • A substantial fraction of breast tumours arising from BRCA1 deficiency are triple negative, representing one of the most aggressive forms of the disease 51. Fig. 1: The functional domains of BRCA1 and BARD1.

   The antitumorigenic roles of BRCA1–BARD1 in DNA repair and ... - Natu…

   www.nature.com/articles/s41580-020-0218-z

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   What is the best prediction model for breast cancer proteins?

   • The current study proposed better prediction models for breast cancer proteins using, as inputs, six sets of protein sequence descriptors from Rcpi and 13 machine-learning classifiers (with or without feature selection/dimension reduction of features). We choose, as the best classifier, the MLP classifier.

   Prediction of breast cancer proteins involved in immunotherapy ... - Nat…

   www.nature.com/articles/s41598-020-65584-y

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   Is BRCA1 a tumour suppressor?

   • BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor protei … The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication Nat Rev Mol Cell Biol. 2020 May;21(5):284-299.doi: 10.1038/s41580-020-0218-z. Epub 2020 Feb 24. Authors

   The antitumorigenic roles of BRCA1-BARD1 in DNA repair and

   pubmed.ncbi.nlm.nih.gov/32094664/

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8. www.nature.com › articles › s41698/019/0103-4Interferon-γ signaling is associated with BRCA1 loss-of ...

   www.nature.com › articles › s41698/019/0103-4

   Dec 6, 2019 · Nature Communications (2022) Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To...

9. www.sciencedirect.com › science › articleComputational structural assessment of BReast CAncer type 1 ...

   www.sciencedirect.com › science › article

   Jan 1, 2022 · Abstract. Breast cancer type 1 susceptibility protein (BRCA1) is closely related to the BRCA2 (breast cancer type 2 susceptibility protein) and BARD1 (BRCA1-associated RING domain-1) proteins.