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  1. Aug 1, 2021 · This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted. After a commissioned evidence-based review by the Agency for Healthcare Research and Quality, an additional extensive and ongoing review of the literature, and supplemental data from published, peer-reviewed studies provided by active ...

  2. Sep 29, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1]. Neonatal sepsis is divided into two groups based on the time of presentation after birth: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis ...

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
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  4. Oct 18, 2023 · Sepsis is an important cause of morbidity and mortality among newborn infants. Although the incidence of sepsis in term and late preterm neonates is low, the potential for serious adverse outcomes is of such great consequence that caregivers should have a low threshold for evaluation and treatment for possible sepsis in neonates.

  5. Apr 1, 2021 · Neonatal infection is a significant cause of mortality and morbidity in newborn babies. It can lead to life-threatening sepsis, which accounts for 10% of all neonatal deaths. Late-onset neonatal infection (infection that occurs more than 72 hours after birth), is present in 7 of every 1000 newborn babies and is responsible for 61 of every 1000 ...

  6. 7. The guidelines group suggests NOT to use a shorter course of intravenous antibiotics (typically 5-7 days) in the management of neonates with uncomplicated@and definite (i.e., culture-positive) neonatal sepsis; these neonates may preferably be treated with the standard course of antibiotics (typically 10-14 days).

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