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Craniodiaphyseal dysplasia ( CDD ), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy . These calcium deposits decrease the size of cranial foramina, and can decrease the circumference of the cervical spinal canal.
- CDD or Lionitis
- Common Symptoms
- Diagnosis – Lionitis Disease
- Treatment Strategies
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Craniofacial hyperostosis: overgrowth of calcium in the bones of the face and skullMassive bone sclerosis: hardening of the bonesDiaphyseal thickening: thickening of the shaft of long bones, such as the femurLionitis Disease affects both sexes and all racial and ethnic groups equally. However, less than one in one million children receive a diagnosis of CDD. Due to this rarity, doctors can only provide a prognosis on a case-by-case basis. While some sufferers have lived to their teen years, most children do not. Additionally, the exact mechanism of inh...
Adopting a low-calcium dietTaking medication to regulate the absorption of calcium in the bodyTaking medication to minimize the growth of cells in charge of bone growthTaking anti-inflammatory drugs to reduce swellingLionitis Disease is a rare genetic disorder that causes excessive hardening of bone, especially in the face and skull. It can lead to intellectual disability, hearing loss, vision problems and other complications. Learn how to recognize the signs, get a diagnosis and access treatment options.
An autosomal dominant or recessive form of craniotubular hyperostosis due to mutation(s) in the SOST gene, encoding sclerostin. This condition is characterized by massive generalized hyperostosis and sclerosis, especially involving the skull and facial bones, which is so severe that the resulting facial distortion is referred to as 'leontiasis ossea'; the bone deposition results in progressive ...
Leontiasis ossea. A 25-year-old man with leontiasis ossea as a complication of polyostotic fibrous dysplasia [1] Leontiasis ossea, also known as leontiasis, lion face or lion face syndrome, is a rare medical condition, characterized by an overgrowth of the facial and cranial bones. It is not a disease in itself, but a symptom of other diseases ...
Dec 31, 2014 · Overview. Craniodiaphyseal dysplasia (also known as CDD or lionitis) is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy.
Nov 6, 2023 · Craniodiaphyseal dysplasia ( CDD ), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy . These calcium deposits decrease the size of cranial foramina, and can decrease the circumference of the cervical spinal canal.
Aug 9, 2013 · Craniodiaphyseal dysplasia Symptoms. There is buildup of calcium within the skull, which reduce the size of cranial foramina. This leads to abnormal facial features and lowers the lifespan of patients. The calcium deposits can also reduce the hole in the cervical spinal canal. There is compression of cranial nerves, the intracranial contents ...
