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  1. Jan 8, 2024 · Tests for Lyme disease involve assessment of either blood samples or CSF, which is the fluid that surrounds the brain and spine. These include: ELISA test: This blood test is used to detect antibodies your body has produced to fight specific pathogens.

  2. Lyme disease is a clinical diagnosis—based on your medical history, symptoms and exposure to ticks. Because the typical Lyme disease diagnostic tests are so insensitive, a negative test result does not mean you don’t have Lyme. There are many reasons why someone who actually has Lyme may have a negative test result.

  3. Aug 15, 2019 · Serologic testing is the principal means of laboratory diagnosis of Lyme disease. Current recommendations include using a sensitive enzyme immunoassay (EIA) or immunofluorescence assay, followed by a western immunoblot assay for specimens yielding positive or equivocal results. What is added by this report?

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