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  1. Jun 30, 2023 · 4 min read. Lyme disease can be tricky to diagnose. The signs and symptoms can look like many other health problems. The ticks that spread it can pass other diseases on to you at the same time....

  2. Diagnosis can be confirmed by serology blood tests which measure the antibodies that are formed by the immune system in response to the Lyme disease bacterial infection. Collection of cerebrospinal fluid by lumbar puncture may be indicated in neurologic cases that may involve the central nervous system.

  3. Feb 10, 2023 · Most people who get Lyme disease don't remember having a tick bite. And many symptoms of Lyme disease relate to other conditions. See your health care provider if you have Lyme disease symptoms.

  4. Lyme disease tests look for signs of infection in a sample of your blood or cerebrospinal fluid (CSF). CSF is a clear liquid that flows in and around your brain and spinal cord. The test checks your sample for antibodies that your immune system makes to fight the bacteria that cause Lyme disease.

  5. Jan 8, 2024 · Tests for Lyme disease involve assessment of either blood samples or CSF, which is the fluid that surrounds the brain and spine. These include: ELISA test: This blood test is used to detect antibodies your body has produced to fight specific pathogens.

  6. Lyme disease is a clinical diagnosis—based on your medical history, symptoms and exposure to ticks. Because the typical Lyme disease diagnostic tests are so insensitive, a negative test result does not mean you don’t have Lyme. There are many reasons why someone who actually has Lyme may have a negative test result.

  7. Jan 19, 2022 · Lyme disease is diagnosed based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks. Laboratory testing is helpful if used correctly and performed with validated methods. Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics.

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