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  1. Jan 8, 2024 · Tests for Lyme disease involve assessment of either blood samples or CSF, which is the fluid that surrounds the brain and spine. These include: ELISA test: This blood test is used to detect antibodies your body has produced to fight specific pathogens.

  2. Lyme disease is a clinical diagnosis—based on your medical history, symptoms and exposure to ticks. Because the typical Lyme disease diagnostic tests are so insensitive, a negative test result does not mean you don’t have Lyme. There are many reasons why someone who actually has Lyme may have a negative test result.

  3. Jan 19, 2022 · Lyme disease is diagnosed based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks. Laboratory testing is helpful if used correctly and performed with validated methods. Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics.

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