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Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. The most common type is known as sickle cell anemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.
- Acute Chest Syndrome
The acute chest syndrome is a vaso-occlusive crisis of the...
- Chromosome 11
Chromosome 11 is one of the 23 pairs of chromosomes in...
- Human genetic resistance to malaria
Sickle-cell disease was the genetic disorder to be linked to...
- Malaria
Several genetic factors provide some resistance to it...
- Acute Chest Syndrome
Oct 9, 2023 · How Does Sickle Cell Protect Against Malaria? People living with sickle cell trait have a significant reduction in the number of malarial parasites living in the body. Children with sickle cell trait and malaria can clear the infection much quicker than those without sickle cell trait.
Feb 9, 2024 · Summary. Both sickle cell disease (SCD) and malaria are potentially dangerous conditions that affect red blood cells (RBCs). While certain forms of SCD may increase the risk of severe...
Jan 14, 2020 · As all infections in the sickle cell population, malaria worsens the preexisting anemia. Malaria was found to be the cause of most severe anaemia in hospitalized patients as demonstrated by Sumbele et al. .
Jan 14, 2020 · It is believed that the current prevalence of malaria in endemic areas reflects selection for the carrier form of sickle cell trait through a survival advantage. Malaria has been incriminated as a great cause of mortality in people with sickle cell disease (SCD).
