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  1. Oct 9, 2022 · Mentha is a perennial, aromatic, and curative herb which has extensive global distribution. Genus Mentha belongs to the family Lamiaceae and comprises 25–30 known species. Mentha grows vigorously at low temperatures but could undergo a wide range of environmental conditions. Normally, it can reach a height of 10 to 20 cm or more.

    • Table 2

      Average activity was recorded from between 10–15 mm...

  2. Apr 1, 2007 · Adults: 0.2 to 0.4 mL of oil three times daily in enteric-coated capsules. Children older than eight years: 0.1 to 0.2 mL three times daily. Cost. $24 to $32 for one-month supply. Bottom line ...

    • $24 to $32 for one-month supply
    • May inhibit the cytochrome P450 1A2 system
  3. Oct 21, 2022 · Mint (Mentha) is a medicinal herb, which possesses a lot of bioactive components. Globally, it has been used as a flavor enhancer in foods. Due to the presence of phenolic acids and flavonoids, it ...

    • Clinical Overview
    • Botany
    • History
    • Chemistry
    • Uses and Pharmacology
    • Dosing
    • Pregnancy / Lactation
    • Interactions
    • Adverse Reactions
    • Toxicology

    Use

    Peppermint, peppermint oil, and its menthol extract have been evaluated for use in GI conditions, including nonserious constipation or diarrhea associated with irritable bowel syndrome (IBS) to reduce global symptoms of pain, and bloating; antispasmodic properties of the oil and menthol extract has led to use in endoscopic GI procedures. Quality clinical trials are lacking to recommend use for treatment of dyspepsia. Menthol, a component of peppermint oil, is often added to respiratory produc...

    Dosing

    Up to 1,200 mg daily (180 to 400 mg 3 times daily) of peppermint oil in enteric-coated capsules has been used to treat nonserious constipation and diarrhea associated with IBS.

    Contraindications

    Peppermint oil should not be administered to patients with gastroesophageal reflux or active gastric ulcers because the oil decreases esophageal sphincter pressure. Peppermint oil should not be applied to the face, especially under the nose of a child or infant. Enteric-coated preparations are not recommended for use in children younger than 8 years.

    Peppermint, a well-known perennial, is a prototypical member of the mint family.USDA 2018 Like all mints, it has a square, purple-green stem with dark- or light-green leaves and purple- and lilac-colored flowers. The plant generally is sterile and spreads by runners. There are a variety of peppermint types cultivated worldwide. Pharmaceutical oil i...

    Peppermint and its oil were first described in England in 1696 and have been used in Eastern and Western traditional medicine as an antispasmodic, aromatic, and antiseptic in the treatment of cancers, colds, cramps, indigestion, nausea, sore throat, and toothaches. Today, the oil is widely used as a flavoring in chewing gum, cigarettes, mouthwash, ...

    Peppermint oil is extracted from the plant by steam distillation.Briggs 1993 The chemistry of peppermint oil is complex and highly variable, with more than 100 components isolated. The relative concentrations vary depending on climate, cultivar, cycle stage, age, season, and geographic location.Ayaz 2017 Oxygenated monoterpenes (79.5%), monoterpene...

    Absorption of menthol is rapid following oral administration, and elimination is mainly via bile.(Yamaguchi 1994) Menthol-glucuronide has been identified as the main metabolite, in addition to mono- or dihydroxylated menthol derivatives.(Grigoleit 2005)

    Various dosages of peppermint oil in enteric-coated capsules have been evaluated for use in GI conditions and procedures.Cash 2016, Grigoleit 2005, Shavakhi 2012, Somerville 1984 Dosages of up to 1,200 mg/day of enteric-coated peppermint oil (capsules containing 180 to 200 mg of peppermint oil and administered as 1 to 2 capsules 3 times daily) over...

    Adverse reactions, particularly with higher doses, have been documented with use of peppermint. Use in pregnancy should be avoided because of emmenagogue effects.Ernst 2002 Peppermint water applied topically has been studied for prevention of nipple cracks in breastfeeding women.Sayyah Melli 2007 Peppermint is reported to be one of the most commonl...

    In a small open-label study, peppermint tea (150 mL consumed 3 times daily for 7 days) significantly reduced the metabolism of nicotine to cotinine in adult smokers of nonmentholated cigarettes (P<0.0001). It is unknown whether peppermint inhibited the CYP2A6 or the aldehyde oxidase step of nicotine metabolism.(Ghazi 2011) Aripiprazole: CYP3A4 inhi...

    Menthol, the major component of peppermint oil, may cause allergic reactions (eg, contact dermatitis, flushing, headache).Herro 2010, Kawane 1996, Leung 1980, Posadzki 2012, Wilkinson 1994 Delayed patch-test reaction to menthol and peppermint oil may occur 6 to 14 days after application.Fleming 1998 Symptoms of contact sensitivity and ulceration fr...

    Like other mints from which menthol is derived as a plant extract, peppermint has GRAS status when consumed as a seasoning or flavoring.McKay 2006, Nair 2001 Two comprehensive reports on peppermint safety have been published,Nair 2001, SCF 2002 with pulegone and menthofuran being the constituents of toxicologic concern. Radiolabeled pulegone binds ...

  4. Dec 21, 2020 · The aim of this paper is to provide an extensive descriptive overview of the medical uses given to these herbs, highlighting both the authors in medical culture responsible for their dissemination, as well as their major galenic formulations. Databases on medical science, reference textbooks on medical history, botanics (aromatic herbs), and ...

    • Henrique Silva
    • 2020
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  6. Oct 9, 2022 · A poor diet, resulting in malnutrition, is a critical challenge that leads to a variety of metabolic disorders, including obesity, diabetes, and cardiovascular diseases. Mentha species are famous as therapeutic herbs and have long served as herbal medicine. Recently, the demand for its products, such as herbal drugs, medicines, and natural herbal formulations, has increased significantly ...

  7. Adult Dose: One softgel three times daily before meals. The dose may be increased to two (2) softgels three times a day when discomfort is more severe. The softgels should be taken until symptoms are relieved. This usually occurs within a week or two. Children's Dose: For children under 15 years of age, consult your physician. Use during Pregnancy:

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