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The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain. The pathway connects the ventral tegmental area in the midbrain to the ventral striatum of the basal ganglia in the forebrain. The ventral striatum includes the nucleus accumbens and the olfactory tubercle.
The four major dopaminergic pathways are the mesolimbic pathway, the mesocortical pathway, the nigrostriatal pathway, and the tuberoinfundibular pathway. The mesolimbic pathway and the mesocortical pathway form the mesocorticolimbic system.
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Daftar Isi. What is the Mesolimbic Pathway? Functions of the Mesolimbic Pathway. The Mesolimbic Pathway and Mental Health. The Neuroscience Behind the Mesolimbic Pathway. Behavioral Aspects of the Mesolimbic Pathway. Everyday Implications of the Mesolimbic Pathway. Conclusion: Harnessing the Mesolimbic Pathway for a Fuller Life. KONSEP UTAMA. FAQ.
Mesolimbic Pathway. The mesolimbic pathway is a collection of dopaminergic neurons that project form the ventral tegmental area (VTA) in the midbrain to the nucleus accumbens (NAc) in the forebrain. From: Drug and Alcohol Dependence, 2021. Related terms: Midbrain; Dopaminergic; Nigrostriatal Pathway; Mesocortical Pathway; Eicosanoid Receptor ...
Its primary input is to the basal ganglia system. Additionally, the mesolimbic pathway projects from the ventral tegmental area to the nucleus accumbens of the ventral striatum. [35] Another well-known afferent is the nigrostriatal connection arising from the neurons of the substantia nigra pars compacta.
- striatum
- D003342
- Ventral striatum, Dorsal striatum
The mesolimbic pathway consists of dopamine neuron somata in the ventral tegmental area and projects to the ventral striatum, also known as the nucleus accumbens, for the control of reward processing. Functions of these pathways are affected in many brain disorders including Parkinson’s disease, schizophrenia and addiction.
The dopaminergic pathway mostly involved in reward is the so-called mesolimbic system, which is formed by projections of midbrain dopamine neurons of the ventral tegmental area (VTA) to the striatum, prefrontal cortex, amygdala, hippocampus, and many other structures of the limbic system.