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  1. A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port.

  2. Aug 9, 2012 · Explore the Mississippi River with American Cruise Lines, the leading operator of river cruises in the US. Choose from 12 itineraries, enjoy modern riverboats with private balconies, and receive free airfare and savings on select dates.

  3. Nov 16, 2023 · Looking for the best Mississippi river cruises? Choose from Viking River Cruises, American Cruise Lines and American Queen Voyages to explore the highlights along the Mighty Mississippi.

  4. Get the latest deals for Mississippi River cruises on Cruise Critic. Find and plan your next cruise to Mississippi River with cabin price comparison, variety of departure ports and...

    • New Orleans, Louisiana, United States. Experience New Orleans, famed for the old-world architecture of its iconic French Quarter.
    • Darrow, Louisiana, United States. Discover the historic architectural treasures of the Lower Mississippi.
    • Baton Rouge, Louisiana, United States. Savor the city’s celebrated Cajun and Creole music and cuisine as well as its distinct arts.
    • St. Francisville, Louisiana, United States. Visit St. Francisville, home to over 140 sites on the National Register of Historic Places.
  5. The ultimate Mississippi cruise - traversing the entire length of the river - stopping at all of the most iconic ports in the region, including New Orleans, Memphis, Hannibal, Winona, and more. Day 1 - New Orleans, LA

  6. Apr 5, 2024 · We've rounded up the best Mississippi River cruises for seniors, history buffs and Americana lovers, so you can find your perfect U.S. river cruise itinerary based on your interests and travel preferences.

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