The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places. A morbilliform rash is a rose-red flat ( macular ) or slightly elevated ( maculopapular ) eruption, showing circular or elliptical lesions varying in diameter from 1 to 3 mm, with healthy-looking skin intervening.
The diagnosis may confirm any number of conditions. The presence of a rash may aid diagnosis; associated signs and symptoms are diagnostic of certain diseases. For example, the rash in measles is an erythematous, morbilliform, maculopapular rash that begins a few days after the fever starts. It classically starts at the head, and spreads downwards.Skin diseaseSymptomsUsual area of bodyComedones, papules, pustules and nodules.Face, chest and back.Flushed appearance or redness.Cheeks, chin, forehead or nose.Painful red bump or a cluster of painful red bumpsAnywhereRed, tender and swollen areas of skinAround a cut, scrape or skin breach
The most common type of eruption is a morbilliform (resembling measles) or erythematous rash (approximately 90% of cases). Less commonly, the appearance may also be urticarial, papulosquamous, pustular, purpuric, bullous (with blisters) or lichenoid. Angioedema can also be drug-induced (most notably, by angiotensin converting enzyme inhibitors).
The rash can also occur in adults. The rash is described as maculopapular or morbilliform (measles-like; therefore, in medical literature, it is called "amoxicillin-induced morbilliform rash".). It starts on the trunk and can spread from there.
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morbilliform (not comparable) (medicine, of a rash) Resembling the erythematous, maculopapular rash of measles. Retrieved from "https: ...
morbilliform rash: An exanthema commonly due to echovirus 9, consisting of fine, discrete maculopapules on the head and neck, rarely elsewhere; the rash and characteristic low-grade fever usually resolve in a week. DiffDx Rubella, meningococcal petechiae-Waterhouse-Friderichsen syndrome, Kawasaki’s disease.
- Signs and symptoms
Morbilliform rash, or \\"measles-like\\" maculopapular skin eruption, is commonly caused by certain drug reactions or viral diseases. Maculopapular rashes are skin eruptions that exhibit both the characteristics of a macule and papule. Macules are small, circumscribed and discolored spots on the skin. The diameter of a macule is not more than .4 inches (10 mm). Papules, on the other hand, are eruptions on the skin, which can look something like a pimple. Morbilliform rashes, therefore, are raised, discolored spots that spread symmetrically across the body.
These rashes may occur due to bacterial infections, drug reactions, and specific or non-specific viral exanthems, also known as viral rashes. A viral exanthem is non-specific if there is no exact information on the virus that has caused the rash. In such a case, the clinician identifies the presence of the virus that is likely to have caused the rash. Morbilliform rash is a \\"late drug rash.\\" It appears on the skin of the affected individual after one to two weeks of exposure to drugs, such as antibiotics or barbiturates. Drug-caused rashes of this kind are usually associated with penicillin, cephalosporins, sulphonamides, and anticonvulsants. Morbilliform rashes often occur in children affected by viral diseases such as measles, Rubella, Roseola, and Erythema infectiosum. In adults, these rashes are usually non-specific viral rashes. This type of rash is also frequently seen in patients who administer ampicillin for the treatment of mononucleosis caused by Epstein-Barr virus or cytomegalovirus. People with human immunodeficiency virus (HIV) tend to develop an acute morbilliform rash when treated with sulfa drugs.
This rash can also appear as a consequence of certain viral diseases. If antibiotics have been started for the patient during the early stages of the viral disease, then the appearance of a morbilliform rash may lead to confusion in diagnosis. Once a drug-induced morbilliform rash is diagnosed, the doctor may ask the patient to discontinue the use of a particular drug.
Usually, oral antihistamines or topical corticosteroids are prescribed for treating these types of rashes. Oral corticosteroids are avoided, as there are chances of the rash to worsen during the steroid therapy, which may lead to the wrong diagnosis. A drug-induced morbilliform rash will usually subside within almost two weeks after the discontinuation of the particular drug. When this type of rash heals, the affected skin sheds or peels, which is also known as skin desquamation.
morbilliform: ( mōr-bil'i-fōrm ), Resembling measles (1). [see morbilli]
Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug.
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